| Reaction Details |
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 | Report a problem with these data |
| Target | Gag polyprotein |
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| Ligand | BDBM50273881 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_536774 (CHEMBL984568) |
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| IC50 | 12000±n/a nM |
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| Citation |  LaFrate, AL; Gunther, JR; Carlson, KE; Katzenellenbogen, JA Synthesis and biological evaluation of guanylhydrazone coactivator binding inhibitors for the estrogen receptor. Bioorg Med Chem16:10075-84 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Gag polyprotein |
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| Name: | Gag polyprotein |
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| Synonyms: | GAG_AVIER | gag |
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| Type: | PROTEIN |
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| Mol. Mass.: | 61664.68 |
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| Organism: | Avian erythroblastosis virus (strain ES4) |
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| Description: | ChEMBL_536774 |
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| Residue: | 555 |
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| Sequence: | REEQVTSEQAKFWLGLGGGRVSPPGPECIEKPATERRIDKGEEMGETTVQRDAKMAPEKM
ATPKTVGTSCYQCGTATGCNCVTASAPPPPYVGSGLYPSLAGAGEQGQGGDTPRGAEQPR
AEPGHAGQAPGPALTDWARIREELASTGPPVVAMPVVIKTEGPAWTPLEPEDTRWLDGKH
KRKSSQCLVKSSMSGYIPSCLDKDEQCVVCGDKATGYHYRCITCEGCKSFFRRTIQKNLH
PTYSCTYDGCCVIDKITRNQCQLCRFKKCISVGMAMDLVLDDSKRVAKRKLIEENRERRR
KEEMIKSLQHRPSPSAEEWELIHVVTEAHRSTNAQGSHWKQRRKFLLEDIGQSPMASMLD
GDKVDLEAFSEFTKIITPAITRVVDFAKNLPMFSELPCEDQIILLKGCCMEIMSLRAAVR
YDPESETLTLSGEMAVKREQLKNGGLGVVSDAIFDLGKSLSAFNLDDTEVALLQAVLLMS
SDRTGLICVDKIEKCQESYLLAFEHYINYRKHNIPHFWSKLLMKVADLRMIGAYHASRFL
HMKVECPTELSPQEV
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| BDBM50273881 |
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| n/a |
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| Name | BDBM50273881 |
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| Synonyms: | 1-(1,1,1,-Trifluoromethyl)-3,4-dihydronaphthalene-2-carboxaldehyde guanylhydrazone | CHEMBL458495 |
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| Type | Small organic molecule |
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| Emp. Form. | C13H13F3N4 |
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| Mol. Mass. | 282.2643 |
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| SMILES | [#7]\[#6](-[#7])=[#7]\[#7]=[#6]-[#6]-1=[#6](-c2ccccc2-[#6]-[#6]-1)C(F)(F)F |w:5.5,t:6| |
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| Structure | 
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