| Reaction Details |
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 | Report a problem with these data |
| Target | Cannabinoid receptor 1 |
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| Ligand | BDBM50256221 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_519285 (CHEMBL947737) |
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| Ki | 624±n/a nM |
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| Citation |  Kai, H; Morioka, Y; Koriyama, Y; Okamoto, K; Hasegawa, Y; Hattori, M; Koike, K; Chiba, H; Shinohara, S; Iwamoto, Y; Takahashi, K; Tanimoto, N 2-Arylimino-5,6-dihydro-4H-1,3-thiazines as a new class of cannabinoid receptor agonists. Part 3: Synthesis and activity of isosteric analogs. Bioorg Med Chem Lett18:6444-7 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cannabinoid receptor 1 |
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| Name: | Cannabinoid receptor 1 |
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| Synonyms: | CANN6 | CANNABINOID CB1 | CB-R | CB1 | CNR | CNR1 | CNR1_HUMAN | Cannabinoid CB1 receptor | Cannabinoid receptor | Cannabinoid receptor 1 (CB1) | Cannabinoid receptor 1 (brain) |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 52868.96 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P21554 |
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| Residue: | 472 |
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| Sequence: | MKSILDGLADTTFRTITTDLLYVGSNDIQYEDIKGDMASKLGYFPQKFPLTSFRGSPFQE
KMTAGDNPQLVPADQVNITEFYNKSLSSFKENEENIQCGENFMDIECFMVLNPSQQLAIA
VLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVF
HRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLM
WTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMYILWK
AHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPLL
AIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTAQ
PLDNSMGDSDCLHKHANNAASVHRAAESCIKSTVKIAKVTMSVSTDTSAEAL
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| BDBM50256221 |
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| n/a |
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| Name | BDBM50256221 |
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| Synonyms: | CHEMBL515604 | S-methyl 3-(naphthalen-1-ylimino)-2,4-diazaspiro[5.5]undecane-2-carbothioate |
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| Type | Small organic molecule |
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| Emp. Form. | C21H25N3OS |
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| Mol. Mass. | 367.508 |
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| SMILES | CSC(=O)N1CC2(CCCCC2)CN=C1Nc1cccc2ccccc12 |c:14| |
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| Structure | 
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