| Reaction Details |
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 | Report a problem with these data |
| Target | Cannabinoid receptor 1 |
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| Ligand | BDBM50213886 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_519288 (CHEMBL947740) |
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| Ki | 6.8±n/a nM |
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| Citation |  Kai, H; Morioka, Y; Koriyama, Y; Okamoto, K; Hasegawa, Y; Hattori, M; Koike, K; Chiba, H; Shinohara, S; Iwamoto, Y; Takahashi, K; Tanimoto, N 2-Arylimino-5,6-dihydro-4H-1,3-thiazines as a new class of cannabinoid receptor agonists. Part 3: Synthesis and activity of isosteric analogs. Bioorg Med Chem Lett18:6444-7 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cannabinoid receptor 1 |
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| Name: | Cannabinoid receptor 1 |
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| Synonyms: | Brain-type cannabinoid receptor | CANNABINOID CB1 | CB-R | CB1 | CNR1_MOUSE | Cannabinoid CB1 receptor | Cannabinoid receptor | Cnr1 |
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| Type: | Enzyme |
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| Mol. Mass.: | 52842.52 |
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| Organism: | Mus musculus (Mouse) |
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| Description: | P47746 |
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| Residue: | 473 |
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| Sequence: | MKSILDGLADTTFRTITTDLLYVGSNDIQYEDIKGDMASKLGYFPQKFPLTSFRGSPFQE
KMTAGDNSPLVPAGDTTNITEFYNKSLSSFKENEDNIQCGENFMDMECFMILNPSQQLAI
AVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFVDFHV
FHRKDSPNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCL
MWTIAIVIAVLPLLGWNCKKLQSVCSDIFPLIDETYLMFWIGVTSVLLLFIVYAYMYILW
KAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPL
LAIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTA
QPLDNSMGDSDCLHKHANNTASMHRAAESCIKSTVKIAKVTMSVSTDTSAEAL
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| BDBM50213886 |
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| n/a |
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| Name | BDBM50213886 |
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| Synonyms: | 3-[(Z)-naphthalen-1-ylimino]-2-thia-4-aza-spiro[5.5]undecane-4-carbodithioic acid methyl ester | CHEMBL232328 | methyl 3-(naphthalen-1-ylimino)-2-thia-4-azaspiro[5.5]undecane-4-carbodithioate |
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| Type | Small organic molecule |
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| Emp. Form. | C21H24N2S3 |
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| Mol. Mass. | 400.624 |
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| SMILES | CSC(=S)N1CC2(CCCCC2)CS\C1=N/c1cccc2ccccc12 |
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| Structure | 
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