| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine receptor A3 |
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| Ligand | BDBM50254649 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_559910 (CHEMBL1011021) |
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| Ki | 65±n/a nM |
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| Citation |  Colotta, V; Capelli, F; Lenzi, O; Catarzi, D; Varano, F; Poli, D; Vincenzi, F; Varani, K; Borea, PA; Dal Ben, D; Volpini, R; Cristalli, G; Filacchioni, G Novel potent and highly selective human A(3) adenosine receptor antagonists belonging to the 4-amido-2-arylpyrazolo[3,4-c]quinoline series: molecular docking analysis and pharmacological studies. Bioorg Med Chem17:401-10 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosine receptor A3 |
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| Name: | Adenosine receptor A3 |
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| Synonyms: | A3 adenosine receptor (hA3) | AA3R_HUMAN | ADORA3 | Adenosine A3 receptor (A3AR) |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 36197.32 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P0DMS8 |
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| Residue: | 318 |
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| Sequence: | MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIA
VGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKR
VTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYF
SFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAFYGREFKTAKSLFLVLFLFA
LSWLPLSIINCIIYFNGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLILKAC
VVCHPSDSLDTSIEKNSE
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| BDBM50254649 |
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| n/a |
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| Name | BDBM50254649 |
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| Synonyms: | CHEMBL463873 | N-(2-phenyl-2H-pyrazolo[3,4-c]quinolin-4-yl)pyrazine-2-carboxamide |
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| Type | Small organic molecule |
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| Emp. Form. | C21H14N6O |
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| Mol. Mass. | 366.3755 |
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| SMILES | O=C(Nc1nc2ccccc2c2cn(nc12)-c1ccccc1)c1cnccn1 |
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| Structure | 
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