| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Arylamine N-acetyltransferase 2 |
|---|
| Ligand | BDBM50274894 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_494097 (CHEMBL942269) |
|---|
| IC50 | >30000±n/a nM |
|---|
| Citation |  Russell, AJ; Westwood, IM; Crawford, MH; Robinson, J; Kawamura, A; Redfield, C; Laurieri, N; Lowe, ED; Davies, SG; Sim, E Selective small molecule inhibitors of the potential breast cancer marker, human arylamine N-acetyltransferase 1, and its murine homologue, mouse arylamine N-acetyltransferase 2. Bioorg Med Chem17:905-18 (2009) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Arylamine N-acetyltransferase 2 |
|---|
| Name: | Arylamine N-acetyltransferase 2 |
|---|
| Synonyms: | ARY2_MOUSE | Aac2 | Nat2 |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 33697.98 |
|---|
| Organism: | Mus musculus |
|---|
| Description: | ChEMBL_1347887 |
|---|
| Residue: | 290 |
|---|
| Sequence: | MDIEAYFERIGYQSTRSKLDLKTLTEILQHQIRAIPFENLNIHCGESMELSLEAIFDQIV
RKKRGGWCLQVNHLLYWALTKLGFETTMLGGYVFNTPANKYSSGMIHLLVQVTISGKDYI
VDAGFGRSYQMWEPLELTSGKDQPQVPAIFRLTEENGTWYLDQIRREQYVPNQEFINSDL
LEKNKYRKIYSFTLEPRTIEDFESMNTYLQTSPASVFTSKSFCSLQTPEGVHCLVGSTLT
YRRFSYKDNVDLVEFKSLTEEEIEDVLRTIFGVSLERKLVPKHGDRFFTI
|
|
|
|---|
| BDBM50274894 |
|---|
| n/a |
|---|
| Name | BDBM50274894 |
|---|
| Synonyms: | (Z)-5-(Naphthalen-1'-ylmethylene)-2-thioxothiazolidin-4-one | (Z)-5-(Naphthalen-1-ylmethylene)-2-thioxothiazolidin-4-one | CHEMBL457747 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C14H9NOS2 |
|---|
| Mol. Mass. | 271.357 |
|---|
| SMILES | SC1=NC(=O)C(S1)=Cc1cccc2ccccc12 |w:7.8,t:1| |
|---|
| Structure | 
|
|---|
Search and Browse
