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TargetCannabinoid receptor 1
LigandBDBM50277266
Substrate/Competitorn/a
Meas. Tech.ChEMBL_540511
Ki 1100±n/a nM
Citation Goodman AJAjello CWWorm KLe Bourdonnec BSavolainen MAO'Hare HCassel JAStabley GJDehaven RNLabuda CJKoblish MLittle PJBrogdon BLSmith SADolle RE CB2 selective sulfamoyl benzamides: optimization of the amide functionality. Bioorg Med Chem Lett 19:309-13 (2008) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Cannabinoid receptor 1
Name:Cannabinoid receptor 1
Synonyms:CANN6 | CANNABINOID CB1 | CB-R | CB1 | CNR | CNR1 | Cannabinoid CB1 receptor | Cannabinoid receptor | Cannabinoid receptor 1 (CB1) | Cannabinoid receptor 1 (brain)
Type:G Protein-Coupled Receptor (GPCR)
Mol. Mass.:52868.96
Organism:Homo sapiens (Human)
Description:P21554
Residue:472
Sequence:
MKSILDGLADTTFRTITTDLLYVGSNDIQYEDIKGDMASKLGYFPQKFPLTSFRGSPFQE
KMTAGDNPQLVPADQVNITEFYNKSLSSFKENEENIQCGENFMDIECFMVLNPSQQLAIA
VLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVF
HRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLM
WTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMYILWK
AHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPLL
AIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTAQ
PLDNSMGDSDCLHKHANNAASVHRAAESCIKSTVKIAKVTMSVSTDTSAEAL
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  Blast E-value cutoff:
BDBM50277266
n/a
NameBDBM50277266
Synonyms:4-(2-methyl-5-(4-neopentyl-1H-imidazol-2-yl)phenylsulfonyl)morpholine | CHEMBL474300
TypeSmall organic molecule
Emp. Form.C19H27N3O3S
Mol. Mass.377.501
SMILESCc1ccc(cc1S(=O)(=O)N1CCOCC1)-c1nc(CC(C)(C)C)c[nH]1
Structure
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