| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Baculoviral IAP repeat-containing protein 2 |
|---|
| Ligand | BDBM50255244 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_516265 (CHEMBL985935) |
|---|
| Ki | 1.27±n/a nM |
|---|
| Citation |  Sun, W; Nikolovska-Coleska, Z; Qin, D; Sun, H; Yang, CY; Bai, L; Qiu, S; Wang, Y; Ma, D; Wang, S Design, synthesis, and evaluation of potent, nonpeptidic mimetics of second mitochondria-derived activator of caspases. J Med Chem52:593-6 (2009) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Baculoviral IAP repeat-containing protein 2 |
|---|
| Name: | Baculoviral IAP repeat-containing protein 2 |
|---|
| Synonyms: | API1 | BIRC2 | BIRC2_HUMAN | Baculoviral IAP repeat-containing protein 2 (cIAP1) | Cellular inhibitor of apoptosis 1 | Inhibitor of apoptosis protein 2 (cIAP1) | MIHB | RNF48 |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 69900.47 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | Q13490 |
|---|
| Residue: | 618 |
|---|
| Sequence: | MHKTASQRLFPGPSYQNIKSIMEDSTILSDWTNSNKQKMKYDFSCELYRMSTYSTFPAGV
PVSERSLARAGFYYTGVNDKVKCFCCGLMLDNWKLGDSPIQKHKQLYPSCSFIQNLVSAS
LGSTSKNTSPMRNSFAHSLSPTLEHSSLFSGSYSSLSPNPLNSRAVEDISSSRTNPYSYA
MSTEEARFLTYHMWPLTFLSPSELARAGFYYIGPGDRVACFACGGKLSNWEPKDDAMSEH
RRHFPNCPFLENSLETLRFSISNLSMQTHAARMRTFMYWPSSVPVQPEQLASAGFYYVGR
NDDVKCFCCDGGLRCWESGDDPWVEHAKWFPRCEFLIRMKGQEFVDEIQGRYPHLLEQLL
STSDTTGEENADPPIIHFGPGESSSEDAVMMNTPVVKSALEMGFNRDLVKQTVQSKILTT
GENYKTVNDIVSALLNAEDEKREEEKEKQAEEMASDDLSLIRKNRMALFQQLTCVLPILD
NLLKANVINKQEHDIIKQKTQIPLQARELIDTILVKGNAAANIFKNCLKEIDSTLYKNLF
VDKNMKYIPTEDVSGLSLEEQLRRLQEERTCKVCMDKEVSVVFIPCGHLVVCQECAPSLR
KCPICRGIIKGTVRTFLS
|
|
|
|---|
| BDBM50255244 |
|---|
| n/a |
|---|
| Name | BDBM50255244 |
|---|
| Synonyms: | (1S,3S,6S,10aS,Z)-1-benzyl-6-((S)-2-(methylamino)propanamido)-5-oxo-N-((R)-1,2,3,4-tetrahydronaphthalen-1-yl)-1,2,3,5,6,7,10,10a-octahydropyrrolo[1,2-a]azocine-3-carboxamide | CHEMBL472832 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C32H40N4O3 |
|---|
| Mol. Mass. | 528.685 |
|---|
| SMILES | CN[C@@H](C)C(=O)N[C@H]1C\C=C/C[C@H]2[C@@H](Cc3ccccc3)C[C@H](N2C1=O)C(=O)N[C@@H]1CCCc2ccccc12 |r,c:9| |
|---|
| Structure | 
|
|---|
Search and Browse
