| Reaction Details |
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 | Report a problem with these data |
| Target | D(3) dopamine receptor |
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| Ligand | BDBM50277037 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_540793 (CHEMBL1033196) |
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| Ki | 172±n/a nM |
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| Citation |  Sikazwe, DM; Nkansah, NT; Altundas, R; Zhu, XY; Roth, BL; Setola, V; Ablordeppey, SY Synthesis and evaluation of ligands for D2-like receptors: the role of common pharmacophoric groups. Bioorg Med Chem17:1716-23 (2009) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| D(3) dopamine receptor |
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| Name: | D(3) dopamine receptor |
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| Synonyms: | DOPAMINE D3 | DRD3 | DRD3_HUMAN | Dopamine D3 receptor | Dopamine D3 receptor (D3) | Dopamine D3 receptor (D3R) | Dopamine receptor | Dopamine receptor (D3) | Dopamine receptor D3 |
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| Type: | n/a |
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| Mol. Mass.: | 44243.43 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 400 |
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| Sequence: | MASLSQLSSHLNYTCGAENSTGASQARPHAYYALSYCALILAIVFGNGLVCMAVLKERAL
QTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILN
LCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPTV
CSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNSQCNSVRPGFPQ
QTLSPDPAHLELKRYYSICQDTALGGPGFQERGGELKREEKTRNSLSPTIAPKLSLEVRK
LSNGRLSTSLKLGPLQPRGVPLREKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHV
SPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC
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| BDBM50277037 |
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| n/a |
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| Name | BDBM50277037 |
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| Synonyms: | 3-(4-Chlorophenyl)-8-(4-fluorobenzyl)-8-azabicyclo[3.2.1]octan-3-ol | CHEMBL456430 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H21ClFNO |
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| Mol. Mass. | 345.838 |
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| SMILES | OC1(CC2CCC(C1)N2Cc1ccc(F)cc1)c1ccc(Cl)cc1 |
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| Structure | 
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