| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Melatonin receptor type 1A |
|---|
| Ligand | BDBM50266405 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_517310 (CHEMBL1031363) |
|---|
| Ki | 132±n/a nM |
|---|
| Citation |  Zlotos, DP; Attia, MI; Julius, J; Sethi, S; Witt-Enderby, PA 2-[(2,3-dihydro-1H-indol-1-yl)methyl]melatonin analogues: a novel class of MT2-selective melatonin receptor antagonists. J Med Chem52:826-33 (2009) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Melatonin receptor type 1A |
|---|
| Name: | Melatonin receptor type 1A |
|---|
| Synonyms: | MTNR1A | MTNR1A protein | MTR1A_HUMAN | Mel-1A-R | Mel1a melatonin receptor | Melatonin 1A | Melatonin receptor | Melatonin receptor 1A | Melatonin receptor type 1 (MT1) | Melatonin receptor type 1A |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 39392.94 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P48039 |
|---|
| Residue: | 350 |
|---|
| Sequence: | MQGNGSALPNASQPVLRGDGARPSWLASALACVLIFTIVVDILGNLLVILSVYRNKKLRN
AGNIFVVSLAVADLVVAIYPYPLVLMSIFNNGWNLGYLHCQVSGFLMGLSVIGSIFNITG
IAINRYCYICHSLKYDKLYSSKNSLCYVLLIWLLTLAAVLPNLRAGTLQYDPRIYSCTFA
QSVSSAYTIAVVVFHFLVPMIIVIFCYLRIWILVLQVRQRVKPDRKPKLKPQDFRNFVTM
FVVFVLFAICWAPLNFIGLAVASDPASMVPRIPEWLFVASYYMAYFNSCLNAIIYGLLNQ
NFRKEYRRIIVSLCTARVFFVDSSNDVADRVKWKPSPLMTNNNVVKVDSV
|
|
|
|---|
| BDBM50266405 |
|---|
| n/a |
|---|
| Name | BDBM50266405 |
|---|
| Synonyms: | CHEMBL457128 | N-(3-(3-methoxyphenyl)-3-(naphthalen-2-yl)propyl)acetamide |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C22H23NO2 |
|---|
| Mol. Mass. | 333.4235 |
|---|
| SMILES | COc1cccc(c1)C(CCNC(C)=O)c1ccc2ccccc2c1 |
|---|
| Structure | 
|
|---|
Search and Browse
