| Reaction Details |
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 | Report a problem with these data |
| Target | Glucose-6-phosphate 1-dehydrogenase |
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| Ligand | BDBM50223368 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_542431 (CHEMBL1011499) |
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| Ki | 8900±n/a nM |
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| Citation |  Cordeiro, AT; Thiemann, OH; Michels, PA Inhibition of Trypanosoma brucei glucose-6-phosphate dehydrogenase by human steroids and their effects on the viability of cultured parasites. Bioorg Med Chem17:2483-9 (2009) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Glucose-6-phosphate 1-dehydrogenase |
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| Name: | Glucose-6-phosphate 1-dehydrogenase |
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| Synonyms: | G6PD | G6PD_HUMAN | Glucose 6-phosphate dehydrogenase (G6PD) | Glucose-6-phosphate 1-dehydrogenase | glucose-6-phosphate 1-dehydrogenase isoform b |
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| Type: | Enzyme |
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| Mol. Mass.: | 59258.58 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P11413 |
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| Residue: | 515 |
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| Sequence: | MAEQVALSRTQVCGILREELFQGDAFHQSDTHIFIIMGASGDLAKKKIYPTIWWLFRDGL
LPENTFIVGYARSRLTVADIRKQSEPFFKATPEEKLKLEDFFARNSYVAGQYDDAASYQR
LNSHMNALHLGSQANRLFYLALPPTVYEAVTKNIHESCMSQIGWNRIIVEKPFGRDLQSS
DRLSNHISSLFREDQIYRIDHYLGKEMVQNLMVLRFANRIFGPIWNRDNIACVILTFKEP
FGTEGRGGYFDEFGIIRDVMQNHLLQMLCLVAMEKPASTNSDDVRDEKVKVLKCISEVQA
NNVVLGQYVGNPDGEGEATKGYLDDPTVPRGSTTATFAAVVLYVENERWDGVPFILRCGK
ALNERKAEVRLQFHDVAGDIFHQQCKRNELVIRVQPNEAVYTKMMTKKPGMFFNPEESEL
DLTYGNRYKNVKLPDAYERLILDVFCGSQMHFVRSDELREAWRIFTPLLHQIELEKPKPI
PYIYGSRGPTEADELMKRVGFQYEGTYKWVNPHKL
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| BDBM50223368 |
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| n/a |
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| Name | BDBM50223368 |
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| Synonyms: | 3beta-hydroxyandrost-5-en-17-one | CHEMBL90593 | DHEAS | Dehydroepiandrosterone (1) | Prasterone |
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| Type | Small organic molecule |
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| Emp. Form. | C19H28O2 |
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| Mol. Mass. | 288.4244 |
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| SMILES | C[C@]12CC[C@H]3[C@@H](CC=C4C[C@@H](O)CC[C@]34C)[C@@H]1CCC2=O |r,t:7| |
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| Structure | 
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