| Reaction Details |
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 | Report a problem with these data |
| Target | Lutropin-choriogonadotropic hormone receptor |
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| Ligand | BDBM50256858 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_562591 (CHEMBL1018020) |
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| IC50 | 2300±n/a nM |
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| Citation |  Heitman, LH; Narlawar, R; de Vries, H; Willemsen, MN; Wolfram, D; Brussee, J; Ijzerman, AP Substituted terphenyl compounds as the first class of low molecular weight allosteric inhibitors of the luteinizing hormone receptor. J Med Chem52:2036-42 (2009) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Lutropin-choriogonadotropic hormone receptor |
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| Name: | Lutropin-choriogonadotropic hormone receptor |
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| Synonyms: | LCGR | LGR2 | LH/CG-R | LHCGR | LHR | LHRHR | LSH-R | LSHR_HUMAN | Luteinizing hormone receptor |
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| Type: | PROTEIN |
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| Mol. Mass.: | 78662.77 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_562598 |
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| Residue: | 699 |
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| Sequence: | MKQRFSALQLLKLLLLLQPPLPRALREALCPEPCNCVPDGALRCPGPTAGLTRLSLAYLP
VKVIPSQAFRGLNEVIKIEISQIDSLERIEANAFDNLLNLSEILIQNTKNLRYIEPGAFI
NLPRLKYLSICNTGIRKFPDVTKVFSSESNFILEICDNLHITTIPGNAFQGMNNESVTLK
LYGNGFEEVQSHAFNGTTLTSLELKENVHLEKMHNGAFRGATGPKTLDISSTKLQALPSY
GLESIQRLIATSSYSLKKLPSRETFVNLLEATLTYPSHCCAFRNLPTKEQNFSHSISENF
SKQCESTVRKVNNKTLYSSMLAESELSGWDYEYGFCLPKTPRCAPEPDAFNPCEDIMGYD
FLRVLIWLINILAIMGNMTVLFVLLTSRYKLTVPRFLMCNLSFADFCMGLYLLLIASVDS
QTKGQYYNHAIDWQTGSGCSTAGFFTVFASELSVYTLTVITLERWHTITYAIHLDQKLRL
RHAILIMLGGWLFSSLIAMLPLVGVSNYMKVSICFPMDVETTLSQVYILTILILNVVAFF
IICACYIKIYFAVRNPELMATNKDTKIAKKMAILIFTDFTCMAPISFFAISAAFKVPLIT
VTNSKVLLVLFYPINSCANPFLYAIFTKTFQRDFFLLLSKFGCCKRRAELYRRKDFSAYT
SNCKNGFTGSNKPSQSTLKLSTLHCQGTALLDKTRYTEC
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| BDBM50256858 |
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| n/a |
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| Name | BDBM50256858 |
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| Synonyms: | CHEMBL474041 | Cyclopentyl-carbamic acid [1,1',3',1'']terphenyl-5'-yl ester |
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| Type | Small organic molecule |
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| Emp. Form. | C24H23NO2 |
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| Mol. Mass. | 357.4449 |
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| SMILES | O=C(NC1CCCC1)Oc1cc(cc(c1)-c1ccccc1)-c1ccccc1 |
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| Structure | 
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