| Reaction Details |
|---|
 | Report a problem with these data |
| Target | 3-dehydroquinate synthase |
|---|
| Ligand | BDBM50028883 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_358 (CHEMBL615413) |
|---|
| KON | 1000 M-1s-1 |
|---|
| Citation |  Montchamp, JL; Piehler, LT; Tolbert, TJ; Front, JW The basis for slowly reversible inhibition of dehydroquinate synthase: a case of mistaken identity? Bioorg Med Chem Lett2:1349-1352 (1992) Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| 3-dehydroquinate synthase |
|---|
| Name: | 3-dehydroquinate synthase |
|---|
| Synonyms: | AROB_ECOLI | aroB |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 38878.02 |
|---|
| Organism: | Escherichia coli (strain K12) |
|---|
| Description: | P07639 |
|---|
| Residue: | 362 |
|---|
| Sequence: | MERIVVTLGERSYPITIASGLFNEPASFLPLKSGEQVMLVTNETLAPLYLDKVRGVLEQA
GVNVDSVILPDGEQYKSLAVLDTVFTALLQKPHGRDTTLVALGGGVVGDLTGFAAASYQR
GVRFIQVPTTLLSQVDSSVGGKTAVNHPLGKNMIGAFYQPASVVVDLDCLKTLPPRELAS
GLAEVIKYGIILDGAFFNWLEENLDALLRLDGPAMAYCIRRCCELKAEVVAADERETGLR
ALLNLGHTFGHAIEAEMGYGNWLHGEAVAAGMVMAARTSERLGQFSSAETQRIITLLKRA
GLPVNGPREMSAQAYLPHMLRDKKVLAGEMRLILPLAIGKSEVRSGVSHELVLNAIADCQ
SA
|
|
|
|---|
| BDBM50028883 |
|---|
| n/a |
|---|
| Name | BDBM50028883 |
|---|
| Synonyms: | (1S,3S,5R)-1,3-Dihydroxy-5-phosphonomethyl-cyclohexanecarboxylic acid | CHEMBL178075 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C8H15O7P |
|---|
| Mol. Mass. | 254.1743 |
|---|
| SMILES | O[C@H]1C[C@@H](CP(O)(O)=O)C[C@](O)(C1)C(O)=O |
|---|
| Structure | 
|
|---|
Search and Browse
