| Reaction Details |
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 | Report a problem with these data |
| Target | 3-dehydroquinate synthase |
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| Ligand | BDBM50280172 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_357 (CHEMBL615412) |
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| KOFF | 0.000750 s-1 |
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| Citation |  Montchamp, JL; Piehler, LT; Tolbert, TJ; Front, JW The basis for slowly reversible inhibition of dehydroquinate synthase: a case of mistaken identity? Bioorg Med Chem Lett2:1349-1352 (1992) Article |
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| More Info.: | Get all data from this article, Assay Method |
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| 3-dehydroquinate synthase |
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| Name: | 3-dehydroquinate synthase |
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| Synonyms: | AROB_ECOLI | aroB |
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| Type: | Enzyme |
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| Mol. Mass.: | 38878.02 |
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| Organism: | Escherichia coli (strain K12) |
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| Description: | P07639 |
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| Residue: | 362 |
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| Sequence: | MERIVVTLGERSYPITIASGLFNEPASFLPLKSGEQVMLVTNETLAPLYLDKVRGVLEQA
GVNVDSVILPDGEQYKSLAVLDTVFTALLQKPHGRDTTLVALGGGVVGDLTGFAAASYQR
GVRFIQVPTTLLSQVDSSVGGKTAVNHPLGKNMIGAFYQPASVVVDLDCLKTLPPRELAS
GLAEVIKYGIILDGAFFNWLEENLDALLRLDGPAMAYCIRRCCELKAEVVAADERETGLR
ALLNLGHTFGHAIEAEMGYGNWLHGEAVAAGMVMAARTSERLGQFSSAETQRIITLLKRA
GLPVNGPREMSAQAYLPHMLRDKKVLAGEMRLILPLAIGKSEVRSGVSHELVLNAIADCQ
SA
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| BDBM50280172 |
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| n/a |
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| Name | BDBM50280172 |
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| Synonyms: | 1,3,4-Trihydroxy-5-phosphonomethyl-cyclohexanecarboxylic acid | CHEMBL281425 |
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| Type | Small organic molecule |
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| Emp. Form. | C8H15O8P |
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| Mol. Mass. | 270.1737 |
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| SMILES | OC1CC(O)(CC(CP(O)(O)=O)C1O)C(O)=O |
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| Structure | 
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