| Reaction Details |
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 | Report a problem with these data |
| Target | Lanosterol 14-alpha demethylase |
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| Ligand | BDBM50280427 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_218337 |
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| Kd | 25000±n/a nM |
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| Citation |  Wright, GD; Honek, JF Synthesis and evaluation of photoaffinity probes directed at lanosterol 14α-demethylase (P-45014DM) Bioorg Med Chem Lett2:383-386 (1992) Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Lanosterol 14-alpha demethylase |
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| Name: | Lanosterol 14-alpha demethylase |
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| Synonyms: | CP51A_HUMAN | CYP51 | CYP51A1 | CYPLI | Cytochrome P450 51 | Cytochrome P450 51A1 | LDM | Lanosterol 14-alpha demethylase | P450-14DM | P45014DM | P450LI | Sterol 14α-demethylase (CYP51) | Sterol 14-alpha demethylase |
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| Type: | Protein |
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| Mol. Mass.: | 56817.21 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q16850 |
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| Residue: | 509 |
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| Sequence: | MAAAAGMLLLGLLQAGGSVLGQAMEKVTGGNLLSMLLIACAFTLSLVYLIRLAAGHLVQL
PAGVKSPPYIFSPIPFLGHAIAFGKSPIEFLENAYEKYGPVFSFTMVGKTFTYLLGSDAA
ALLFNSKNEDLNAEDVYSRLTTPVFGKGVAYDVPNPVFLEQKKMLKSGLNIAHFKQHVSI
IEKETKEYFESWGESGEKNVFEALSELIILTASHCLHGKEIRSQLNEKVAQLYADLDGGF
SHAAWLLPGWLPLPSFRRRDRAHREIKDIFYKAIQKRRQSQEKIDDILQTLLDATYKDGR
PLTDDEVAGMLIGLLLAGQHTSSTTSAWMGFFLARDKTLQKKCYLEQKTVCGENLPPLTY
DQLKDLNLLDRCIKETLRLRPPIMIMMRMARTPQTVAGYTIPPGHQVCVSPTVNQRLKDS
WVERLDFNPDRYLQDNPASGEKFAYVPFGAGRHRCIGENFAYVQIKTIWSTMLRLYEFDL
IDGYFPTVNYTTMIHTPENPVIRYKRRSK
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| BDBM50280427 |
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| n/a |
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| Name | BDBM50280427 |
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| Synonyms: | 1-(4-Azido-phenyl)-1H-imidazole | CHEMBL127685 |
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| Type | Small organic molecule |
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| Emp. Form. | C9H7N5 |
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| Mol. Mass. | 185.1854 |
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| SMILES | [N-]=[N+]=Nc1ccc(cc1)-n1ccnc1 |
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| Structure | 
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