| Reaction Details |
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 | Report a problem with these data |
| Target | Pepsin A |
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| Ligand | BDBM50280489 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_154163 |
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| Ki | 40000±n/a nM |
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| Citation |  Schirlin, D; Tarnus, C; Baltzer, S; Rémy, JM MDL 74147, a novel selective and soluble inhibitor of human renin. Synthesis, structure-activity relationship, species and protease selectivities. Bioorg Med Chem Lett2:651-654 (1992) Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Pepsin A |
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| Name: | Pepsin A |
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| Synonyms: | PEPA_PIG | PGA | Pepsin | Pepsin A precursor |
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| Type: | Enzyme |
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| Mol. Mass.: | 41232.87 |
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| Organism: | Porcine |
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| Description: | n/a |
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| Residue: | 385 |
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| Sequence: | MKWLLLLSLVVLSECLVKVPLVRKKSLRQNLIKNGKLKDFLKTHKHNPASKYFPEAAALI
GDEPLENYLDTEYFGTIGIGTPAQDFTVIFDTGSSNLWVPSVYCSSLACSDHNQFNPDDS
STFEATSQELSITYGTGSMTGILGYDTVQVGGISDTNQIFGLSETEPGSFLYYAPFDGIL
GLAYPSISASGATPVFDNLWDQGLVSQDLFSVYLSSNDDSGSVVLLGGIDSSYYTGSLNW
VPVSVEGYWQITLDSITMDGETIACSGGCQAIVDTGTSLLTGPTSAIANIQSDIGASENS
DGEMVISCSSIDSLPDIVFTINGVQYPLSPSAYILQDDDSCTSGFEGMDVPTSSGELWIL
GDVFIRQYYTVFDRANNKVGLAPVA
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| BDBM50280489 |
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| n/a |
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| Name | BDBM50280489 |
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| Synonyms: | (S)-2-[(S)-3-(4-Methoxy-phenyl)-2-(3-methyl-butyrylamino)-propionylamino]-pentanoic acid ((S)-4-amino-1-cyclohexylmethyl-3,3-difluoro-2-oxo-butyl)-amide; hydrochloride | CHEMBL555920 |
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| Type | Small organic molecule |
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| Emp. Form. | C31H48F2N4O5 |
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| Mol. Mass. | 594.7334 |
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| SMILES | CCC[C@H](NC(=O)[C@H](Cc1ccc(OC)cc1)NC(=O)CC(C)C)C(=O)N[C@@H](CC1CCCCC1)C(=O)C(F)(F)CN |r| |
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| Structure | 
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