| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Muscarinic acetylcholine receptor M1 |
|---|
| Ligand | BDBM50280523 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_139204 |
|---|
| IC50 | 2800±n/a nM |
|---|
| Citation |  Sanders, KB; Thomas, AJ; Pavia, MR; Davis, RE; Coughenour, LL; Myers, SL; Fisher, S; Moos, WH Cholinergic agents: aldehyde, ketone, and oxime analogues of the muscarinic agonist UH5 Bioorg Med Chem Lett2:803-808 (1992) Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Muscarinic acetylcholine receptor M1 |
|---|
| Name: | Muscarinic acetylcholine receptor M1 |
|---|
| Synonyms: | ACM1_HUMAN | CHRM1 | Cholinergic receptor, muscarinic 1 | Cholinergic, muscarinic M1 |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 51442.54 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P11229 |
|---|
| Residue: | 460 |
|---|
| Sequence: | MNTSAPPAVSPNITVLAPGKGPWQVAFIGITTGLLSLATVTGNLLVLISFKVNTELKTVN
NYFLLSLACADLIIGTFSMNLYTTYLLMGHWALGTLACDLWLALDYVASNASVMNLLLIS
FDRYFSVTRPLSYRAKRTPRRAALMIGLAWLVSFVLWAPAILFWQYLVGERTVLAGQCYI
QFLSQPIITFGTAMAAFYLPVTVMCTLYWRIYRETENRARELAALQGSETPGKGGGSSSS
SERSQPGAEGSPETPPGRCCRCCRAPRLLQAYSWKEEEEEDEGSMESLTSSEGEEPGSEV
VIKMPMVDPEAQAPTKQPPRSSPNTVKRPTKKGRDRAGKGQKPRGKEQLAKRKTFSLVKE
KKAARTLSAILLAFILTWTPYNIMVLVSTFCKDCVPETLWELGYWLCYVNSTINPMCYAL
CNKAFRDTFRLLLLCRWDKRRWRKIPKRPGSVHRTPSRQC
|
|
|
|---|
| BDBM50280523 |
|---|
| n/a |
|---|
| Name | BDBM50280523 |
|---|
| Synonyms: | 3-Methyl-7-pyrrolidin-1-yl-hept-5-yn-2-one | CHEMBL353023 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C12H19NO |
|---|
| Mol. Mass. | 193.2854 |
|---|
| SMILES | CC(CC#CCN1CCCC1)C(C)=O |
|---|
| Structure | 
|
|---|
Search and Browse
