| Reaction Details |
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 | Report a problem with these data |
| Target | Muscarinic acetylcholine receptor M2 |
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| Ligand | BDBM50280574 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_139630 |
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| IC50 | 4460±n/a nM |
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| Citation |  Tecle, H; Mirzadegan, T; Moos, WH; Moreland, DW; Pavia, MR; Schwarz, RD; Davis, RE A rationale for the design and synthesis of m1 selective muscarinic agonists. Bioorg Med Chem Lett2:821-826 (1992) Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Muscarinic acetylcholine receptor M2 |
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| Name: | Muscarinic acetylcholine receptor M2 |
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| Synonyms: | ACM2_HUMAN | CHRM2 | Cholinergic, muscarinic M2 | Muscarinic acetylcholine receptor M2 and M4 | Muscarinic acetylcholine receptor M2 and M5 | RecName: Full=Muscarinic acetylcholine receptor M2 |
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| Type: | GPCR |
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| Mol. Mass.: | 51730.61 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P08172 |
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| Residue: | 466 |
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| Sequence: | MNNSTNSSNNSLALTSPYKTFEVVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNY
FLFSLACADLIIGVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFD
RYFCVTKPLTYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTVEDGECYIQF
FSNAAVTFGTAIAAFYLPVIIMTVLYWHISRASKSRIKKDKKEPVANQDPVSPSLVQGRI
VKPNNNNMPSSDDGLEHNKIQNGKAPRDPVTENCVQGEEKESSNDSTSVSAVASNMRDDE
ITQDENTVSTSLGHSKDENSKQTCIRIGTKTPKSDSCTPTNTTVEVVGSSGQNGDEKQNI
VARKIVKMTKQPAKKKPPPSREKKVTRTILAILLAFIITWAPYNVMVLINTFCAPCIPNT
VWTIGYWLCYINSTINPACYALCNATFKKTFKHLLMCHYKNIGATR
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| BDBM50280574 |
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| n/a |
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| Name | BDBM50280574 |
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| Synonyms: | 1-Aza-bicyclo[2.2.1]heptan-3-one O-tert-butyl-oxime | CHEMBL166593 |
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| Type | Small organic molecule |
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| Emp. Form. | C10H18N2O |
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| Mol. Mass. | 182.2627 |
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| SMILES | CC(C)(C)O\N=C1/CN2CCC1C2 |THB:5:6:12:10.9| |
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| Structure | 
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