| Reaction Details |
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 | Report a problem with these data |
| Target | Phospholipase A2, membrane associated |
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| Ligand | BDBM50000541 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_155877 |
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| IC50 | >1000000±n/a nM |
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| Citation |  Wright, SW; Pinto, DJ; Sherk, SR; Green, AM; Magolda, RL Vinylogous hydroxamic acids: 5-lipoxygenase inhibitors Bioorg Med Chem Lett2:1079-1084 (1992) Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Phospholipase A2, membrane associated |
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| Name: | Phospholipase A2, membrane associated |
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| Synonyms: | GIIC sPLA2 | Group IIA phospholipase A2 | NPS-PLA2 | Non-Pancreatic Secretory Phospholipase A2 | Non-pancreatic secretory phospholipase A2 (hnps-PLA2) | PA2GA_HUMAN | PLA2B | PLA2G2A | PLA2L | Phosphatidylcholine 2-acylhydrolase | Phospholipase A2 group IIA | RASF-A |
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| Type: | Hydrolase |
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| Mol. Mass.: | 16101.20 |
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| Organism: | Homo sapiens (Human) |
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| Description: | The human nps PLA2 was cloned, and expressed in E. coli. There was a refolding process in the purification. |
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| Residue: | 144 |
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| Sequence: | MKTLLLLAVIMIFGLLQAHGNLVNFHRMIKLTTGKEAALSYGFYGCHCGVGGRGSPKDAT
DRCCVTHDCCYKRLEKRGCGTKFLSYKFSNSGSRITCAKQDSCRSQLCECDKAAATCFAR
NKTTYNKKYQYYSNKHCRGSTPRC
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| BDBM50000541 |
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| n/a |
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| Name | BDBM50000541 |
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| Synonyms: | (+-)-1-(1-Benzo[b]thien-2-ylethyl)-1-hydroxyurea | 1-[1-(1-benzothien-2-yl)ethyl]-1-hydroxyurea | CHEMBL93 | Leutrol | N-(1-Benzo(b)thien-2-ylethyl)-N-hydroxyurea | N-[1-(benzo[b]thiophen-2-yl)ethyl]-N-hydroxyurea | ZILEUTON | Zyflo (TN) |
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| Type | Small organic molecule |
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| Emp. Form. | C11H12N2O2S |
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| Mol. Mass. | 236.29 |
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| SMILES | CC(N(O)C(N)=O)c1cc2ccccc2s1 |
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| Structure | 
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