| Reaction Details |
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 | Report a problem with these data |
| Target | 3-phosphoshikimate 1-carboxyvinyltransferase |
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| Ligand | BDBM50281345 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_65094 |
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| IC50 | >90000000±n/a nM |
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| Citation |  Corey, SD; Pansegrau, PD; Walker, MC; Sikorski, JA EPSP synthase inhibitor deisgn III. Synthesis & evaluation of a new 5-oxamic acid analog of EPSP which incorporates a malonate ether as a 3-phosphate mimic Bioorg Med Chem Lett3:2857-2862 (1993) Article |
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| More Info.: | Get all data from this article, Assay Method |
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| 3-phosphoshikimate 1-carboxyvinyltransferase |
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| Name: | 3-phosphoshikimate 1-carboxyvinyltransferase |
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| Synonyms: | 5-enolpyruvylshikimate-3-phosphate synthase | AROA_ECOLI | aroA |
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| Type: | PROTEIN |
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| Mol. Mass.: | 46089.22 |
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| Organism: | Escherichia coli (strain K12) |
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| Description: | ChEMBL_65087 |
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| Residue: | 427 |
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| Sequence: | MESLTLQPIARVDGTINLPGSKSVSNRALLLAALAHGKTVLTNLLDSDDVRHMLNALTAL
GVSYTLSADRTRCEIIGNGGPLHAEGALELFLGNAGTAMRPLAAALCLGSNDIVLTGEPR
MKERPIGHLVDALRLGGAKITYLEQENYPPLRLQGGFTGGNVDVDGSVSSQFLTALLMTA
PLAPEDTVIRIKGDLVSKPYIDITLNLMKTFGVEIENQHYQQFVVKGGQSYQSPGTYLVE
GDASSASYFLAAAAIKGGTVKVTGIGRNSMQGDIRFADVLEKMGATICWGDDYISCTRGE
LNAIDMDMNHIPDAAMTIATAALFAKGTTTLRNIYNWRVKETDRLFAMATELRKVGAEVE
EGHDYIRITPPEKLNFAEIATYNDHRMAMCFSLVALSDTPVTILDPKCTAKTFPDYFEQL
ARISQAA
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| BDBM50281345 |
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| n/a |
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| Name | BDBM50281345 |
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| Synonyms: | (3R,4R,5R)-5-Carboxymethoxy-3,4-dihydroxy-cyclohex-1-enecarboxylic acid | 5-Carboxymethoxy-3,4-dihydroxy-cyclohex-1-enecarboxylic acid | CHEMBL32446 |
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| Type | Small organic molecule |
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| Emp. Form. | C9H12O7 |
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| Mol. Mass. | 232.1874 |
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| SMILES | O[C@@H]1C=C(C[C@@H](OCC(O)=O)[C@@H]1O)C(O)=O |c:2| |
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| Structure | 
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