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TargetCholecystokinin receptor type A
LigandBDBM50281717
Substrate/Competitorn/a
Meas. Tech.ChEBML_50203
IC50 28±n/a nM
Citation Bock, MGDiPardo, RMVeber, DFChang, RSLotti, VJFreedman, SBFreidinger, RM Benzolactams as non-peptide cholecystokinin receptor ligands Bioorg Med Chem Lett3:871-874 (1993)    Article
More Info.:Get all data from this article,  Assay Method
 
Cholecystokinin receptor type A
Name:Cholecystokinin receptor type A
Synonyms:CCKAR_RAT | Cckar | Cholecystokinin peripheral | Cholecystokinin receptor | Cholecystokinin receptor type A
Type:Enzyme Catalytic Domain
Mol. Mass.:49676.37
Organism:RAT
Description:Cholecystokinin central 0 RAT::P30551
Residue:444
Sequence:
MSHSPARQHLVESSRMDVVDSLLMNGSNITPPCELGLENETLFCLDQPQPSKEWQSALQI
LLYSIIFLLSVLGNTLVITVLIRNKRMRTVTNIFLLSLAVSDLMLCLFCMPFNLIPNLLK
DFIFGSAVCKTTTYFMGTSVSVSTFNLVAISLERYGAICRPLQSRVWQTKSHALKVIAAT
WCLSFTIMTPYPIYSNLVPFTKNNNQTANMCRFLLPSDAMQQSWQTFLLLILFLLPGIVM
VVAYGLISLELYQGIKFDASQKKSAKEKKPSTGSSTRYEDSDGCYLQKSRPPRKLELQQL
SSGSGGSRLNRIRSSSSAANLIAKKRVIRMLIVIVVLFFLCWMPIFSANAWRAYDTVSAE
KHLSGTPISFILLLSYTSSCVNPIIYCFMNKRFRLGFMATFPCCPNPGPPGVRGEVGEEE
DGRTIRALLSRYSYSHMSTSAPPP
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BDBM50281717
n/a
NameBDBM50281717
Synonyms:1-(3-Methoxy-phenyl)-3-[(R)-2-oxo-1-(2-oxo-2-pyrrolidin-1-yl-ethyl)-2,3,4,5-tetrahydro-1H-benzo[b]azepin-3-yl]-urea | CHEMBL354442
TypeSmall organic molecule
Emp. Form.C24H28N4O4
Mol. Mass.436.5035
SMILESCOc1cccc(NC(=O)N[C@@H]2CCc3ccccc3N(CC(=O)N3CCCC3)C2=O)c1
Structure
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