| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Lanosterol synthase |
|---|
| Ligand | BDBM50281884 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_148884 |
|---|
| IC50 | 420±n/a nM |
|---|
| Citation |  Wannamaker, M; Waid, PP; Moore, WR; Schatzman, GL; Van Sickle, WA; Wilson, PK Inhibition of 2,3-oxidosqualene cyclase by N-alkylpiperidines Bioorg Med Chem Lett3:1175-1178 (1993) Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Lanosterol synthase |
|---|
| Name: | Lanosterol synthase |
|---|
| Synonyms: | LSS_RAT | Lss | Osc |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 83302.12 |
|---|
| Organism: | Rattus norvegicus |
|---|
| Description: | ChEMBL_12083 |
|---|
| Residue: | 733 |
|---|
| Sequence: | MTEGTCLRRRGGPYKTEPATDLTRWRLHNELGRQRWTYYQAEEDPGREQTGLEAHSLGLD
TTSYFKNLPKAQTAHEGALNGVTFYAKLQAEDGHWAGDYGGPLFLLPGLLITCHIAHIPL
PAGYREEMVRYLRSVQLPDGGWGLHIEDKSTVFGTALSYVSLRILGIGPDDPDLVRARNI
LHKKGGAVAIPSWGKFWLAVLNVYSWEGINTLFPEMWLLPEWFPAHPSTLWCHCRQVYLP
MSYCYATRLSASEDPLVQSLRQELYVEDYASIDWPAQKNNVCPDDMYTPHSWLLHVVYGL
LNLYERFHSTSLRKWAIQLLYEHVAADDRFTKCISIGPISKTVNMLIRWSVDGPSSPAFQ
EHVSRIKDYLWLGLDGMKMQGTNGSQTWDTSFAVQALLEAGAHRRPEFLPCLQKAHEFLR
LSQVPDNNPDYQKYYRHMHKGGFPFSTLDCGWIVADCTAEALKAVLLLQERCPSITEHVP
RERLYDAVAVLLSMRNSDGGFATYETKRGGYLLELLNPSEVFGDIMIDYTYVECTSAVMQ
ALRHFREYFPDHRATESRETLNQGLDFCRKKQRADGSWEGSWGVCFTYGTWFGLEAFACM
GHIYQNRTACAEVAQACHFLLSRQMADGGWGEDFESCEQRRYVQSAGSQVHSTCWALLGL
MAVRHPDISAQERGIRCLLGKQLPNGDWPQENISGVFNKSCAISYTNYRNIFPIWALGRF
SSLYPDNTLAGHI
|
|
|
|---|
| BDBM50281884 |
|---|
| n/a |
|---|
| Name | BDBM50281884 |
|---|
| Synonyms: | 2-(1-Dodecyl-piperidin-4-yl)-propan-1-ol | CHEMBL17737 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C20H41NO |
|---|
| Mol. Mass. | 311.5456 |
|---|
| SMILES | CCCCCCCCCCCCN1CCC(CC1)C(C)CO |
|---|
| Structure | 
|
|---|
Search and Browse
