| Reaction Details |
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 | Report a problem with these data |
| Target | Squalene monooxygenase |
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| Ligand | BDBM50281968 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_201934 |
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| IC50 | 13000±n/a nM |
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| Citation |  Anstead, GM; Lin, HK; Prestwich, GD Trisnorsqualene methyl hydroxylamine: a potent dual inhibitor of mammalian squalene epoxidase and oxidosqualene cyclase Bioorg Med Chem Lett3:1319-1322 (1993) Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Squalene monooxygenase |
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| Name: | Squalene monooxygenase |
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| Synonyms: | ERG1 | ERG1_HUMAN | SE | SQLE | Squalene epoxidase |
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| Type: | PROTEIN |
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| Mol. Mass.: | 63936.94 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_201924 |
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| Residue: | 574 |
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| Sequence: | MWTFLGIATFTYFYKKFGDFITLANREVLLCVLVFLSLGLVLSYRCRHRNGGLLGRQQSG
SQFALFSDILSGLPFIGFFWAKSPPESENKEQLEARRRRKGTNISETSLIGTAACTSTSS
QNDPEVIIVGAGVLGSALAAVLSRDGRKVTVIERDLKEPDRIVGEFLQPGGYHVLKDLGL
GDTVEGLDAQVVNGYMIHDQESKSEVQIPYPLSENNQVQSGRAFHHGRFIMSLRKAAMAE
PNAKFIEGVVLQLLEEDDVVMGVQYKDKETGDIKELHAPLTVVADGLFSKFRKSLVSNKV
SVSSHFVGFLMKNAPQFKANHAELILANPSPVLIYQISSSETRVLVDIRGEMPRNLREYM
VEKIYPQIPDHLKEPFLEATDNSHLRSMPASFLPPSSVKKRGVLLLGDAYNMRHPLTGGG
MTVAFKDIKLWRKLLKGIPDLYDDAAIFEAKKSFYWARKTSHSFVVNILAQALYELFSAT
DDSLHQLRKACFLYFKLGGECVAGPVGLLSVLSPNPLVLIGHFFAVAIYAVYFCFKSEPW
ITKPRALLSSGAVLYKACSVIFPLIYSEMKYMVH
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| BDBM50281968 |
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| n/a |
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| Name | BDBM50281968 |
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| Synonyms: | CHEMBL9533 | N-Methyl-N-((4E,12E,16E,20E)-4,8,13,17,21-pentamethyl-docosa-4,8,12,16,20-pentaenyl)-hydroxylamine |
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| Type | Small organic molecule |
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| Emp. Form. | C28H49NO |
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| Mol. Mass. | 415.6948 |
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| SMILES | [#6]-[#7](-[#8])-[#6]-[#6]-[#6]\[#6](-[#6])=[#6]\[#6]-[#6]\[#6](-[#6])=[#6]\[#6]-[#6]\[#6]=[#6](/[#6])-[#6]-[#6]\[#6]=[#6](/[#6])-[#6]-[#6]\[#6]=[#6](\[#6])-[#6] |
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| Structure | 
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