| Reaction Details |
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 | Report a problem with these data |
| Target | 3-phosphoshikimate 1-carboxyvinyltransferase |
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| Ligand | BDBM50281996 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_64958 |
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| IC50 | >90000000±n/a nM |
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| Citation |  Miller, MJ; Anderson, KS; Braccolino, DS; Cleary, DG; Gruys, KJ; Han, CY; Lin, KC; Pansegrau, PD; Ream, JE; Sammons, RD; Sikorski, JA EPSP synthase inhibitor design II. The importance of the 3-phosphate group for ligand binding at the shikimate-3-phosphate site & the identification of 3-malonate ethers as novel 3-phosphate mimics. Bioorg Med Chem Lett3:1435-1440 (1993) Article |
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| More Info.: | Get all data from this article, Assay Method |
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| 3-phosphoshikimate 1-carboxyvinyltransferase |
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| Name: | 3-phosphoshikimate 1-carboxyvinyltransferase |
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| Synonyms: | 5-enolpyruvylshikimate-3-phosphate synthase | AROA_ECOLI | aroA |
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| Type: | PROTEIN |
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| Mol. Mass.: | 46089.22 |
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| Organism: | Escherichia coli (strain K12) |
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| Description: | ChEMBL_65087 |
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| Residue: | 427 |
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| Sequence: | MESLTLQPIARVDGTINLPGSKSVSNRALLLAALAHGKTVLTNLLDSDDVRHMLNALTAL
GVSYTLSADRTRCEIIGNGGPLHAEGALELFLGNAGTAMRPLAAALCLGSNDIVLTGEPR
MKERPIGHLVDALRLGGAKITYLEQENYPPLRLQGGFTGGNVDVDGSVSSQFLTALLMTA
PLAPEDTVIRIKGDLVSKPYIDITLNLMKTFGVEIENQHYQQFVVKGGQSYQSPGTYLVE
GDASSASYFLAAAAIKGGTVKVTGIGRNSMQGDIRFADVLEKMGATICWGDDYISCTRGE
LNAIDMDMNHIPDAAMTIATAALFAKGTTTLRNIYNWRVKETDRLFAMATELRKVGAEVE
EGHDYIRITPPEKLNFAEIATYNDHRMAMCFSLVALSDTPVTILDPKCTAKTFPDYFEQL
ARISQAA
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| BDBM50281996 |
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| n/a |
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| Name | BDBM50281996 |
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| Synonyms: | 2-(3-Carboxy-cyclohex-2-enyl)-malonic acid | CHEMBL33336 |
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| Type | Small organic molecule |
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| Emp. Form. | C10H12O6 |
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| Mol. Mass. | 228.1987 |
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| SMILES | OC(=O)C(C1CCCC(=C1)C(O)=O)C(O)=O |c:8| |
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| Structure | 
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