| Reaction Details |
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 | Report a problem with these data |
| Target | Type-2 angiotensin II receptor |
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| Ligand | BDBM50283244 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_35562 |
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| IC50 | 0.690000±n/a nM |
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| Citation |  Santella, JB; Duncia, JV; Ensinger, CL; VanAtten, MK; Carini, DJ; Wexler, RR; Chiu, AT; Wong, PC; Timmermans, PB Balanced angiotensin II receptor antagonists. III. The effects of substitution at the imidazole 5-position. Bioorg Med Chem Lett4:2235-2240 (1994) Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Type-2 angiotensin II receptor |
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| Name: | Type-2 angiotensin II receptor |
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| Synonyms: | AGTR2 | AGTR2_HUMAN | AT2 | Angiotensin II receptor | Angiotensin II type 2 (AT-2) receptor | Angiotensin II, central | Type-2 angiotensin II receptor |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 41201.61 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Angiotensin II, central 0 0::P50052 |
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| Residue: | 363 |
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| Sequence: | MKGNSTLATTSKNITSGLHFGLVNISGNNESTLNCSQKPSDKHLDAIPILYYIIFVIGFL
VNIVVVTLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVF
GSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYIVPLVWCMACLSSLPTFY
FRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLK
TNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALAWMGVINSCEVIAVIDLAL
PFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFRVPITWLQGKRESMSCRKSSSLREMET
FVS
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| BDBM50283244 |
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| n/a |
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| Name | BDBM50283244 |
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| Synonyms: | Biphenylsulfonylcarbamate compound | CHEMBL71125 |
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| Type | Small organic molecule |
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| Emp. Form. | C45H42FN3O7S |
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| Mol. Mass. | 787.894 |
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| SMILES | CCCc1nc(CC)c(C(=O)OCc2ccccc2C(=O)c2ccccc2)n1Cc1ccc(cc1F)-c1ccccc1S(=O)(=O)NC(=O)OCCc1ccccc1 |
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| Structure | 
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