| Reaction Details |
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 | Report a problem with these data |
| Target | Stromelysin-1 |
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| Ligand | BDBM50101506 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_102089 |
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| Ki | 952±n/a nM |
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| Citation |  Morphy, JR; Beeley, NR; Boyce, BA; Leonard, J; Mason, B; Millican, A; Millar, K; O'Connell, JP; Porter, J Potent and selective inhibitors of gelatinase-A 2. carboxylic and phosphonic acid derivatives Bioorg Med Chem Lett4:2747-2752 (1994) Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Stromelysin-1 |
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| Name: | Stromelysin-1 |
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| Synonyms: | MMP-3 | MMP3 | MMP3_HUMAN | Matrix metalloproteinase (2 and 3) | Matrix metalloproteinase 3 | Matrix metalloproteinase-3 | Matrix metalloproteinase-3 (MMP-3) | Matrix metalloproteinase-3 (MMP3) | SL-1 | STMY1 | Stromelysin 1 | Transin-1 |
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| Type: | Enzyme |
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| Mol. Mass.: | 53973.13 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P08254 |
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| Residue: | 477 |
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| Sequence: | MKSLPILLLLCVAVCSAYPLDGAARGEDTSMNLVQKYLENYYDLKKDVKQFVRRKDSGPV
VKKIREMQKFLGLEVTGKLDSDTLEVMRKPRCGVPDVGHFRTFPGIPKWRKTHLTYRIVN
YTPDLPKDAVDSAVEKALKVWEEVTPLTFSRLYEGEADIMISFAVREHGDFYPFDGPGNV
LAHAYAPGPGINGDAHFDDDEQWTKDTTGTNLFLVAAHEIGHSLGLFHSANTEALMYPLY
HSLTDLTRFRLSQDDINGIQSLYGPPPDSPETPLVPTEPVPPEPGTPANCDPALSFDAVS
TLRGEILIFKDRHFWRKSLRKLEPELHLISSFWPSLPSGVDAAYEVTSKDLVFIFKGNQF
WAIRGNEVRAGYPRGIHTLGFPPTVRKIDAAISDKEKNKTYFFVEDKYWRFDEKRNSMEP
GFPKQIAEDFPGIDSKIDAVFEEFGFFYFFTGSSQLEFDPNAKKVTHTLKSNSWLNC
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| BDBM50101506 |
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| n/a |
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| Name | BDBM50101506 |
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| Synonyms: | (R)-3-{(S)-2-cyclohexyl-1-[2-(4-sulfamoyl-phenyl)-ethylcarbamoyl]-ethylcarbamoyl}-6-phenyl-hexanoic acid | 3-{2-Cyclohexyl-1-[2-(4-sulfamoyl-phenyl)-ethylcarbamoyl]-ethylcarbamoyl}-6-phenyl-hexanoic acid | CHEMBL432346 |
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| Type | Small organic molecule |
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| Emp. Form. | C30H41N3O6S |
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| Mol. Mass. | 571.728 |
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| SMILES | NS(=O)(=O)c1ccc(CCNC(=O)[C@H](CC2CCCCC2)NC(=O)[C@H](CCCc2ccccc2)CC(O)=O)cc1 |
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| Structure | 
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