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TargetStromelysin-1
LigandBDBM50101515
Substrate/Competitorn/a
Meas. Tech.ChEBML_102089
Ki 472±n/a nM
Citation Morphy, JRBeeley, NRBoyce, BALeonard, JMason, BMillican, AMillar, KO'Connell, JPPorter, J Potent and selective inhibitors of gelatinase-A 2. carboxylic and phosphonic acid derivatives Bioorg Med Chem Lett4:2747-2752 (1994)    Article
More Info.:Get all data from this article,  Assay Method
 
Stromelysin-1
Name:Stromelysin-1
Synonyms:MMP-3 | MMP3 | MMP3_HUMAN | Matrix metalloproteinase (2 and 3) | Matrix metalloproteinase 3 | Matrix metalloproteinase-3 | Matrix metalloproteinase-3 (MMP-3) | Matrix metalloproteinase-3 (MMP3) | SL-1 | STMY1 | Stromelysin 1 | Transin-1
Type:Enzyme
Mol. Mass.:53973.13
Organism:Homo sapiens (Human)
Description: P08254
Residue:477
Sequence:
MKSLPILLLLCVAVCSAYPLDGAARGEDTSMNLVQKYLENYYDLKKDVKQFVRRKDSGPV
VKKIREMQKFLGLEVTGKLDSDTLEVMRKPRCGVPDVGHFRTFPGIPKWRKTHLTYRIVN
YTPDLPKDAVDSAVEKALKVWEEVTPLTFSRLYEGEADIMISFAVREHGDFYPFDGPGNV
LAHAYAPGPGINGDAHFDDDEQWTKDTTGTNLFLVAAHEIGHSLGLFHSANTEALMYPLY
HSLTDLTRFRLSQDDINGIQSLYGPPPDSPETPLVPTEPVPPEPGTPANCDPALSFDAVS
TLRGEILIFKDRHFWRKSLRKLEPELHLISSFWPSLPSGVDAAYEVTSKDLVFIFKGNQF
WAIRGNEVRAGYPRGIHTLGFPPTVRKIDAAISDKEKNKTYFFVEDKYWRFDEKRNSMEP
GFPKQIAEDFPGIDSKIDAVFEEFGFFYFFTGSSQLEFDPNAKKVTHTLKSNSWLNC
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  Blast E-value cutoff:
BDBM50101515
n/a
NameBDBM50101515
Synonyms:(R)-3-(((S)-3-cyclohexyl-1-oxo-1-(phenethylamino)propan-2-yl)carbamoyl)-6-p-tolylhexanoic acid | (R)-3-((S)-2-Cyclohexyl-1-phenethylcarbamoyl-ethylcarbamoyl)-6-p-tolyl-hexanoic acid | 3-(2-Cyclohexyl-1-phenethylcarbamoyl-ethylcarbamoyl)-6-p-tolyl-hexanoic acid | CHEMBL307365
TypeSmall organic molecule
Emp. Form.C31H42N2O4
Mol. Mass.506.6762
SMILESCc1ccc(CCC[C@H](CC(O)=O)C(=O)N[C@@H](CC2CCCCC2)C(=O)NCCc2ccccc2)cc1
Structure
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