| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Cysteinyl leukotriene receptor 1 |
|---|
| Ligand | BDBM50284683 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_99989 |
|---|
| Ki | 23400±n/a nM |
|---|
| Citation |  Masamune, H; Eggler, JF; Marfat, A; Melvin, LS; Rusek, FW; Tickner, JE; Cheng, JB; Shirley, JT LTD4 Receptor binding activity of novel pyridine chromanols: qualitative correlation with pKa Bioorg Med Chem Lett5:1371-1376 (1995) Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Cysteinyl leukotriene receptor 1 |
|---|
| Name: | Cysteinyl leukotriene receptor 1 |
|---|
| Synonyms: | CLTR1_CAVPO | CYSLTR1 |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 39007.58 |
|---|
| Organism: | GUINEA PIG |
|---|
| Description: | Leukotriene D4 0 GUINEA PIG::Q2NNR5 |
|---|
| Residue: | 340 |
|---|
| Sequence: | MDETGNPTIPPASNNTCYDSIDDFRNQVYSTLYSMISVVGFFGNGFVLYVLVKTYHEKSA
FQVYMINLAVADLLCVCTLPLRVAYYVHKGIWLFGDFLCRLSTYALYVNLYCSIFFMTAM
SFFRCVAIVFPVQNISLVTQKKARLVCIAIWMFVILTSSPFLMANTYKDEKNNTKCFEPP
QDNQAKNYVLILHYVSLFIGFIIPFITIIVCYTMIIFTLLKSSMKKNLSSRKRAIGMIIV
VTAAFLVSFMPYHIQRTIHLHFLHNKTKPCDSILRMQKSVVITLSLAASNCCFDPLLYFF
SGGNFRRRLSTIRKYSLSSMTYIPKKKTSLPQKGKDICKE
|
|
|
|---|
| BDBM50284683 |
|---|
| n/a |
|---|
| Name | BDBM50284683 |
|---|
| Synonyms: | (3S,4S)-6-(6-Chloro-pyridin-2-ylmethoxy)-3-pyridin-3-ylmethyl-chroman-4-ol | CHEMBL29937 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C21H19ClN2O3 |
|---|
| Mol. Mass. | 382.84 |
|---|
| SMILES | O[C@H]1[C@@H](Cc2cccnc2)COc2ccc(OCc3cccc(Cl)n3)cc12 |
|---|
| Structure | 
|
|---|
Search and Browse
