Reaction Details | |||
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Target | Squalene synthase | ||
Ligand | BDBM50038096 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | ChEBML_202260 | ||
Ki | 0.078±n/a nM | ||
Citation | Chiang, YP; Kurtz, MM; Bergstrom, JD; Berger, GD 3,4-Diesters of zaragozic acid A Bioorg Med Chem Lett5:1643-1646 (1995) Article | ||
More Info.: | Get all data from this article, Assay Method | ||
Squalene synthase | |||
Name: | Squalene synthase | ||
Synonyms: | FDFT_RAT | FPP:FPP farnesyltransferase | Farnesyl-diphosphate farnesyltransferase | Fdft1 | SQS | SS | Squalene synthetase | ||
Type: | PROTEIN | ||
Mol. Mass.: | 48109.41 | ||
Organism: | Rattus norvegicus | ||
Description: | ChEMBL_1336736 | ||
Residue: | 416 | ||
Sequence: |
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BDBM50038096 | |||
n/a | |||
Name | BDBM50038096 | ||
Synonyms: | (6R,7R)-1-((4S,5R)-4-Acetoxy-5-methyl-3-methylene-6-phenyl-hexyl)-6-((E)-(4S,6S)-4,6-dimethyl-oct-2-enoyloxy)-4,7-dihydroxy-2,8-dioxa-bicyclo[3.2.1]octane-3,4,5-tricarboxylic acid | (R)-1-((4S,5R)-4-Acetoxy-5-methyl-3-methylene-6-phenyl-hexyl)-6-((E)-(4S,6S)-4,6-dimethyl-oct-2-enoyloxy)-4,7-dihydrxxy-2,8-dioxa-bicyclo[3.2.1]octane-3,4,5-tricarboxylic acid | 7-[3,5-dimethyl-(E,3S,5S)-1-heptenylcarbonyloxy]-2,6-dihydroxy-5-{3-[2-methyl-1-methylcarbonyloxy-3-phenyl-(1S,2R)-propyl]-3-butenyl}-(6R,7R)-4,8-dioxabicyclo[3.2.1]octane-1,2,3-tricarboxylic acid | CHEMBL40991 | L-694599 | ||
Type | Small organic molecule | ||
Emp. Form. | C35H46O14 | ||
Mol. Mass. | 690.7313 | ||
SMILES | CC[C@H](C)C[C@H](C)\C=C\C(=O)O[C@@H]1[C@@H](O)C2(CCC(=C)[C@@H](OC(C)=O)[C@H](C)Cc3ccccc3)OC1(C(O)=O)C(O)(C(O2)C(O)=O)C(O)=O | ||
Structure |