| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Platelet-activating factor receptor |
|---|
| Ligand | BDBM50286038 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_155151 |
|---|
| Ki | 54±n/a nM |
|---|
| Citation |  Sheppard, GS; Davidsen, SK; Carrera, GM; Pireh, D; Holms, JH; Heyman, HR; Steinman, DH; Curtin, ML; Conway, RG; Rhein, DA; Albert, DH; Tapang, P; Magoc, TJ; Summers, JB Synthesis and evaluation of water soluble indole pyrrolothiazole paf antagonists Bioorg Med Chem Lett5:2913-2918 (1995) Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Platelet-activating factor receptor |
|---|
| Name: | Platelet-activating factor receptor |
|---|
| Synonyms: | PAF-R | PTAFR | PTAFR_CAVPO | Platelet activating factor receptor | Platelet-activating factor receptor |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 39005.63 |
|---|
| Organism: | Cavia porcellus |
|---|
| Description: | n/a |
|---|
| Residue: | 342 |
|---|
| Sequence: | MELNSSSRVDSEFRYTLFPIVYSIIFVLGIIANGYVLWVFARLYPSKKLNEIKIFMVNLT
VADLLFLITLPLWIVYYSNQGNWFLPKFLCNLAGCLFFINTYCSVAFLGVITYNRFQAVK
YPIKTAQATTRKRGIALSLVIWVAIVAAASYFLVMDSTNVVSNKAGSGNITRCFEHYEKG
SKPVLIIHICIVLGFFIVFLLILFCNLVIIHTLLRQPVKQQRNAEVRRRALWMVCTVLAV
FVICFVPHHMVQLPWTLAELGMWPSSNHQAINDAHQVTLCLLSTNCVLDPVIYCFLTKKF
RKHLSEKLNIMRSSQKCSRVTTDTGTEMAIPINHTPVNPIKN
|
|
|
|---|
| BDBM50286038 |
|---|
| n/a |
|---|
| Name | BDBM50286038 |
|---|
| Synonyms: | (S)-2-Amino-3-{4-[1-dimethylcarbamoyl-3-((R)-3-pyridin-3-yl-1H-pyrrolo[1,2-c]thiazole-7-carbonyl)-1H-indol-6-yl]-phenyl}-propionic acid | CHEMBL330219 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C32H29N5O4S |
|---|
| Mol. Mass. | 579.669 |
|---|
| SMILES | CN(C)C(=O)n1cc(C(=O)c2ccn3[C@H](SCc23)c2cccnc2)c2ccc(cc12)-c1ccc(C[C@H](N)C(O)=O)cc1 |
|---|
| Structure | 
|
|---|
Search and Browse
