| Reaction Details |
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 | Report a problem with these data |
| Target | Platelet-activating factor receptor |
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| Ligand | BDBM50286037 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_155151 |
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| Ki | 450±n/a nM |
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| Citation |  Sheppard, GS; Davidsen, SK; Carrera, GM; Pireh, D; Holms, JH; Heyman, HR; Steinman, DH; Curtin, ML; Conway, RG; Rhein, DA; Albert, DH; Tapang, P; Magoc, TJ; Summers, JB Synthesis and evaluation of water soluble indole pyrrolothiazole paf antagonists Bioorg Med Chem Lett5:2913-2918 (1995) Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Platelet-activating factor receptor |
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| Name: | Platelet-activating factor receptor |
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| Synonyms: | PAF-R | PTAFR | PTAFR_CAVPO | Platelet activating factor receptor | Platelet-activating factor receptor |
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| Type: | Protein |
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| Mol. Mass.: | 39005.63 |
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| Organism: | Cavia porcellus |
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| Description: | n/a |
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| Residue: | 342 |
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| Sequence: | MELNSSSRVDSEFRYTLFPIVYSIIFVLGIIANGYVLWVFARLYPSKKLNEIKIFMVNLT
VADLLFLITLPLWIVYYSNQGNWFLPKFLCNLAGCLFFINTYCSVAFLGVITYNRFQAVK
YPIKTAQATTRKRGIALSLVIWVAIVAAASYFLVMDSTNVVSNKAGSGNITRCFEHYEKG
SKPVLIIHICIVLGFFIVFLLILFCNLVIIHTLLRQPVKQQRNAEVRRRALWMVCTVLAV
FVICFVPHHMVQLPWTLAELGMWPSSNHQAINDAHQVTLCLLSTNCVLDPVIYCFLTKKF
RKHLSEKLNIMRSSQKCSRVTTDTGTEMAIPINHTPVNPIKN
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| BDBM50286037 |
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| n/a |
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| Name | BDBM50286037 |
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| Synonyms: | 6-(4-Fluoro-phenyl)-3-{((R)-3-pyridin-3-yl-1H-pyrrolo[1,2-c]thiazol-7-yl)-[(Z)-3-pyrrolidin-1-yl-propoxyimino]-methyl}-indole-1-carboxylic acid dimethylamide | CHEMBL316463 |
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| Type | Small organic molecule |
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| Emp. Form. | C36H37FN6O2S |
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| Mol. Mass. | 636.781 |
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| SMILES | CN(C)C(=O)n1cc(\C(=N\OCCCN2CCCC2)c2ccn3[C@H](SCc23)c2cccnc2)c2ccc(cc12)-c1ccc(F)cc1 |
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| Structure | 
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