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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Substance-P receptor | ||
| Ligand | BDBM50286409 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEBML_208671 | ||
| IC50 | 5700±n/a nM | ||
| Citation |  Barrow, CJ; Musza, LL; Cooper, R Structure-activity studies of the natural product substance P antagonist win 64821 Bioorg Med Chem Lett5:377-380 (1995) Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Substance-P receptor | |||
| Name: | Substance-P receptor | ||
| Synonyms: | NK-1 receptor | NK-1R | NK1 Receptor | NK1R | NK1R_HUMAN | Neurokinin 1 receptor | Neurokinin-1 (NK-1) | Neuromedin-1 receptor (NK-1R) | SPR | TAC1R | TACR1 | Tachykinin receptor 1 | Tachykinin receptor 1 (NK1) | tachykinin | ||
| Type: | G Protein-Coupled Receptor (GPCR) | ||
| Mol. Mass.: | 46254.43 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P25103 | ||
| Residue: | 407 | ||
| Sequence: |
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| BDBM50286409 | |||
| n/a | |||
| Name | BDBM50286409 | ||
| Synonyms: | (3S,5aR,11aS,3'S,5'aR,11'aS)-3,3'-Dibenzyl-10,10'-dimethyl-2,3,5a,6,11,11a,2',3',5'a,6',11',11'a-dodecahydro-[10b,10'b]bi[pyrazino[1',2':1,5]pyrrolo[2,3-b]indolyl]-1,4,1',4'-tetraone | CHEMBL124979 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C42H40N6O4 | ||
| Mol. Mass. | 692.8048 | ||
| SMILES | Cc1cccc2N[C@@H]3N4[C@@H](CC3(c12)C12C[C@@H]3N([C@H]1Nc1cccc(C)c21)C(=O)[C@H](Cc1ccccc1)NC3=O)C(=O)N[C@@H](Cc1ccccc1)C4=O | ||
| Structure | 
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