| Reaction Details |
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 | Report a problem with these data |
| Target | Cannabinoid receptor 1/2 |
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| Ligand | BDBM50068669 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_46141 (CHEMBL660014) |
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| IC50 | 10000±n/a nM |
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| Citation |  Kumar, V; Alexander, MD; Bell, MR; Eissenstat, MA; Casiano, FM; Chippari, SM; Haycock, DA; Luttinger, DA; Kuster, JE; Miller, MS; Stevenson, JI; Ward, SJ Morpholinoalkylindenes as antinociceptive agents: Novel cannabinoid receptor agonists Bioorg Med Chem Lett5:381-386 (1995) Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cannabinoid receptor 1/2 |
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| Name: | Cannabinoid receptor 1/2 |
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| Synonyms: | Cannabinoid receptor |
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| Type: | n/a |
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| Mol. Mass.: | n/a |
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| Description: | ASSAY_ID of ChEMBL is 1859866 |
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| Components: | This complex has 2 components. |
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| Component 1 |
| Name: | Cannabinoid receptor 2 |
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| Synonyms: | CANNABINOID CB2 | CB-2 | CB2 | CNR2_RAT | Cannabinoid CB2 receptor | Cannabinoid receptor | Cnr2 | rCB2 |
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| Type: | Enzyme |
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| Mol. Mass.: | 39366.68 |
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| Organism: | Rattus norvegicus (Rat) |
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| Description: | Q9QZN9 |
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| Residue: | 360 |
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| Sequence: | MAGCRELELTNGSNGGLEFNPMKEYMILSDAQQIAVAVLCTLMGLLSALENVAVLYLILS
SQRLRRKPSYLFIGSLAGADFLASVIFACNFVIFHVFHGVDSRNIFLLKIGSVTMTFTAS
VGSLLLTAVDRYLCLCYPPTYKALVTRGRALVALGVMWVLSALISYLPLMGWTCCPSPCS
ELFPLIPNDYLLGWLLFIAILFSGIIYTYGYVLWKAHQHVASLAEHQDRQVPGIARMRLD
VRLAKTLGLVMAVLLICWFPALALMGHSLVTTLSDKVKEAFAFCSMLCLVNSMINPIIYA
LRSGEIRSAAQHCLTGWKKYLQGLGSEGKEEAPKSSVTETEAEVKTTTGPGSRTPGCSNC
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| Component 2 |
| Name: | Cannabinoid receptor 1 |
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| Synonyms: | Brain-type cannabinoid receptor | CANNABINOID CB1 | CB-R | CB1 | CNR1_RAT | Cannabinoid CB1 receptor | Cannabinoid receptor | Cannabinoid receptor 1 (CB1) | Cnr1 | Skr6 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 52856.55 |
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| Organism: | Rattus norvegicus (rat) |
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| Description: | P20272 |
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| Residue: | 473 |
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| Sequence: | MKSILDGLADTTFRTITTDLLYVGSNDIQYEDIKGDMASKLGYFPQKFPLTSFRGSPFQE
KMTAGDNSPLVPAGDTTNITEFYNKSLSSFKENEENIQCGENFMDMECFMILNPSQQLAI
AVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFVDFHV
FHRKDSPNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCL
MWTIAIVIAVLPLLGWNCKKLQSVCSDIFPLIDETYLMFWIGVTSVLLLFIVYAYMYILW
KAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPL
LAIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTA
QPLDNSMGDSDCLHKHANNTASMHRAAESCIKSTVKIAKVTMSVSTDTSAEAL
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| BDBM50068669 |
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| n/a |
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| Name | BDBM50068669 |
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| Synonyms: | 4-(2-{2-Methyl-3-[1-naphthalen-1-yl-meth-(Z)-ylidene]-3H-inden-1-yl}-ethyl)-morpholine | CHEMBL123916 |
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| Type | Small organic molecule |
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| Emp. Form. | C27H27NO |
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| Mol. Mass. | 381.5094 |
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| SMILES | CC1=C(CCN2CCOCC2)c2ccccc2\C1=C\c1cccc2ccccc12 |c:1| |
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| Structure | 
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