| Reaction Details |
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 | Report a problem with these data |
| Target | Dopamine beta-hydroxylase |
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| Ligand | BDBM50286812 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_59304 |
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| Ki | 1060000±n/a nM |
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| Citation |  Eydoux, F; Chlenov, MA; Réglier, M Synthesis of indane derivatives as mechanism-based inhibitors of dopamine β-hydroxylase Bioorg Med Chem Lett5:941-944 (1995) Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Dopamine beta-hydroxylase |
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| Name: | Dopamine beta-hydroxylase |
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| Synonyms: | DBH | DOPO_BOVIN |
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| Type: | PROTEIN |
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| Mol. Mass.: | 68136.39 |
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| Organism: | Bos taurus |
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| Description: | ChEMBL_50738 |
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| Residue: | 610 |
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| Sequence: | MQVPSPSVREAASMYGTAVAVFLVILVAALQGSAPAESPFPFHIPLDPEGTLELSWNISY
AQETIYFQLLVRELKAGVLFGMSDRGELENADLVVLWTDRDGAYFGDAWSDQKGQVHLDS
QQDYQLLRAQRTPEGLYLLFKRPFGTCDPNDYLIEDGTVHLVYGFLEEPLRSLESINTSG
LHTGLQRVQLLKPSIPKPALPADTRTMEIRAPDVLIPGQQTTYWCYVTELPDGFPRHHIV
MYEPIVTEGNEALVHHMEVFQCAAEFETIPHFSGPCDSKMKPQRLNFCRHVLAAWALGAK
AFYYPEEAGLAFGGPGSSRFLRLEVHYHNPLVITGRRDSSGIRLYYTAALRRFDAGIMEL
GLAYTPVMAIPPQETAFVLTGYCTDKCTQLALPASGIHIFASQLHTHLTGRKVVTVLARD
GRETEIVNRDNHYSPHFQEIRMLKKVVSVQPGDVLITSCTYNTEDRRLATVGGFGILEEM
CVNYVHYYPQTQLELCKSAVDPGFLHKYFRLVNRFNSEEVCTCPQASVPEQFASVPWNSF
NREVLKALYGFAPISMHCNRSSAVRFQGEWNRQPLPEIVSRLEEPTPHCPASQAQSPAGP
TVLNISGGKG
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| BDBM50286812 |
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| n/a |
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| Name | BDBM50286812 |
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| Synonyms: | 6,6a-Dihydro-1aH-1-oxa-cyclopropa[a]indene | CHEMBL170741 |
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| Type | Small organic molecule |
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| Emp. Form. | C9H8O |
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| Mol. Mass. | 132.1592 |
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| SMILES | C1C2OC2c2ccccc12 |
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| Structure | 
|
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