| Reaction Details |
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 | Report a problem with these data |
| Target | Acetylcholinesterase |
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| Ligand | BDBM50286924 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_27806 |
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| IC50 | >1000000±n/a nM |
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| Citation |  Holan, G; Virgona, CT; Watson, KG; Finkelstein, BL Synthesis, insecticidal and anti-acetylcholinesterase activity of a new class of heterocyclic methanesulfonates Bioorg Med Chem Lett6:77-80 (1996) Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Acetylcholinesterase |
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| Name: | Acetylcholinesterase |
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| Synonyms: | ACES_BOVIN | ACHE | Acetylcholinesterase (AChE) | Acetylcholinesterase precursor |
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| Type: | Enzyme |
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| Mol. Mass.: | 67659.62 |
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| Organism: | Bos taurus (bovine) |
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| Description: | n/a |
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| Residue: | 613 |
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| Sequence: | MRPPWCPLHTPSLTPPLLLLLFLIGGGAEAEGPEDPELLVMVRGGRLRGLRLMAPRGPVS
AFLGIPFAEPPVGPRRFLPPEPKRPWPGVLNATAFQSVCYQYVDTLYPGFEGTEMWNPNR
ELSEDCLYLNVWTPYPRPSSPTPVLVWIYGGGFYSGASSLDVYDGRFLTQAEGTVLVSMN
YRVGAFGFLALPGSREAPGNVGLLDQRLALQWVQENVAAFGGDPTSVTLFGESAGAASVG
MHLLSPPSRGLFHRAVLQSGAPNGPWATVGVGEARRRATLLARLVGCPPGGAGGNDTELV
ACLRARPAQDLVDHEWRVLPQESVFRFSFVPVVDGDFLSDTPEALINAGDFHGLQVLVGV
VKDEGSYFLVYGAPGFSKDNESLISRAQFLAGVRVGVPQASDLAAEAVVLHYTDWLHPED
PARLREALSDVVGDHNVVCPVAQLAGRLAAQGARVYAYIFEHRASTLSWPLWMGVPHGYE
IEFIFGLPLEPSLNYTIEERTFAQRLMRYWANFARTGDPNDPRDPKAPQWPPYTAGAQQY
VSLNLRPLEVRRGLRAQACAFWNRFLPKLLSATDTLDEAERQWKAEFHRWSSYMVHWKNQ
FDHYSKQDRCSDL
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| BDBM50286924 |
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| n/a |
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| Name | BDBM50286924 |
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| Synonyms: | 3-Methanesulfonyloxy-5,5-dimethyl-4,5-dihydro-pyrazole-1-carboxylic acid ethyl ester | CHEMBL168127 |
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| Type | Small organic molecule |
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| Emp. Form. | C9H16N2O5S |
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| Mol. Mass. | 264.299 |
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| SMILES | CCOC(=O)N1N=C(CC1(C)C)OS(C)(=O)=O |c:6| |
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| Structure | 
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