| Reaction Details |
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 | Report a problem with these data |
| Target | Gag-Pol polyprotein [489-587] |
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| Ligand | BDBM50287015 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_159443 |
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| IC50 | 5370±n/a nM |
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| Citation |  Prasad, JV; Pavlovsky, A; Para, KS; Ellsworth, EL; Tummino, PJ; Nouhan, C; Ferguson, D Nonpeptidic HIV protease inhibitors: 3-(S-benzyl substituted)-4-hydroxy-6-(phenyl substituted)-2H-pyran-2-one with an inverse mode of binding Bioorg Med Chem Lett6:1133-1138 (1996) Article |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Gag-Pol polyprotein [489-587] |
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| Name: | Gag-Pol polyprotein [489-587] |
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| Synonyms: | Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol |
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| Type: | Enzyme Subunit |
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| Mol. Mass.: | 10781.16 |
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| Organism: | Human immunodeficiency virus type 1 |
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| Description: | P04585[489-587] |
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| Residue: | 99 |
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| Sequence: | PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYD
QILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
|
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|
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| BDBM50287015 |
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| n/a |
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| Name | BDBM50287015 |
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| Synonyms: | 4-Hydroxy-3-(2-methyl-benzylsulfanyl)-6-phenyl-pyran-2-one | CHEMBL278942 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H16O3S |
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| Mol. Mass. | 324.394 |
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| SMILES | Cc1ccccc1CSc1c(O)cc(oc1=O)-c1ccccc1 |
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| Structure | 
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