Reaction Details |
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Target | Gag-Pol polyprotein [489-587] |
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Ligand | BDBM50287042 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEBML_159443 |
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IC50 | 14160±n/a nM |
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Citation | Prasad, JV; Pavlovsky, A; Para, KS; Ellsworth, EL; Tummino, PJ; Nouhan, C; Ferguson, D Nonpeptidic HIV protease inhibitors: 3-(S-benzyl substituted)-4-hydroxy-6-(phenyl substituted)-2H-pyran-2-one with an inverse mode of binding Bioorg Med Chem Lett6:1133-1138 (1996) Article |
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More Info.: | Get all data from this article, Assay Method |
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Gag-Pol polyprotein [489-587] |
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Name: | Gag-Pol polyprotein [489-587] |
Synonyms: | Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol |
Type: | Enzyme Subunit |
Mol. Mass.: | 10781.16 |
Organism: | Human immunodeficiency virus type 1 |
Description: | P04585[489-587] |
Residue: | 99 |
Sequence: | PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYD
QILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
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BDBM50287042 |
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n/a |
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Name | BDBM50287042 |
Synonyms: | 3-Benzylsulfanyl-4-hydroxy-6-o-tolyl-pyran-2-one | CHEMBL14698 |
Type | Small organic molecule |
Emp. Form. | C19H16O3S |
Mol. Mass. | 324.394 |
SMILES | Cc1ccccc1-c1cc(O)c(SCc2ccccc2)c(=O)o1 |
Structure |
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