| Reaction Details |
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 | Report a problem with these data |
| Target | Sodium- and chloride-dependent GABA transporter 2 |
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| Ligand | BDBM50403566 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_70051 |
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| IC50 | 669000±n/a nM |
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| Citation |  Dhar, TG; Nakanishi, H; Borden, LA; Gluchowski, C On the bioactive conformation of the gaba uptake inhibitor SK&F 89976-A Bioorg Med Chem Lett6:1535-1540 (1996) Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Sodium- and chloride-dependent GABA transporter 2 |
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| Name: | Sodium- and chloride-dependent GABA transporter 2 |
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| Synonyms: | GABA transporter | GABA transporter 2 | Gabt2 | Gat-2 | S6A13_RAT | Slc6a13 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 68261.89 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_70051 |
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| Residue: | 602 |
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| Sequence: | MDNRVSGTTSNGETKPVCPVMEKVEEDGTLEREQWTNKMEFVLSVAGEIIGLGNVWRFPY
LCYKNGGGAFFIPYLIFLFTCGIPVFFLETALGQYTNQGGITAWRKICPIFEGIGYASQM
IVSLLNVYYIVVLAWALFYLFSSFTTDLPWGSCSHEWNTENCVEFQKTNNSLNVTSENAT
SPVIEFWERRVLKISDGIQHLGSLRWELVLCLLLAWIICYFCIWKGVKSTGKVVYFTATF
PYLMLVVLLIRGVTLPGAAQGIQFYLYPNITRLWDPQVWMDAGTQIFFSFAICLGCLTAL
GSYNKYHNNCYRDCVALCILNSSTSFVAGFAIFSILGFMSQEQGVPISEVAESGPGLAFI
AYPRAVVMLPFSPLWACCFFFMVVLLGLDSQFVCVESLVTALVDMYPRVFRKKNRREILI
LIVSVVSFFIGLIMLTEGGMYVFQLFDYYAASGMCLLFVAIFESLCVAWVYGASRFYDNI
EDMIGYKPWPLIKYCWLFFTPAVCLATFLFSLIKYTPLTYNKKYTYPWWGDALGWLLALS
SMVCIPAWSIYKLRTLKGPLRERLRQLVCPAEDLPQKSQPELTSPATPMTSLLRLTELES
NC
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| BDBM50403566 |
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| n/a |
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| Name | BDBM50403566 |
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| Synonyms: | CHEMBL2094022 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H27NO2 |
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| Mol. Mass. | 349.466 |
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| SMILES | OC(=O)[C@H]1CCC2C[C@@H](CCN2C1)C(c1ccccc1)c1ccccc1 |r| |
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| Structure | 
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