| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Reverse transcriptase/RNaseH |
|---|
| Ligand | BDBM50288063 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_195046 |
|---|
| IC50 | >100000±n/a nM |
|---|
| Citation |  Weaver, R; Gilbert, IH; Mahmood, N; Balzarini, J Isosteres of nucleoside triphosphates Bioorg Med Chem Lett6:2405-2410 (1996) Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Reverse transcriptase/RNaseH |
|---|
| Name: | Reverse transcriptase/RNaseH |
|---|
| Synonyms: | HIV-1 Reverse Transcriptase RNase H | Human immunodeficiency virus type 1 reverse transcriptase | Reverse transcriptase/RNaseH |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 65229.15 |
|---|
| Organism: | Human immunodeficiency virus 1 |
|---|
| Description: | ChEMBL_1473730 |
|---|
| Residue: | 566 |
|---|
| Sequence: | PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKRKSVTVLDVGDAYFSVPL
DEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI
YQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIRVRQLCKLLRGTKALTEVIPLTEEAE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLRTGKYARMRGA
HTNDVKQLTEAVQKITTESIVIWGKTPKFKLPIQKETWETWWTEYWQATWIPEWEFVNTP
PLVKLWYQLEKEPIVGAETFYVDGAANRETKLGKAGYVTNRGRQKVVTLTDTTNQKTELQ
AIYLALQDSGLEVNIVTDSQYALGIIQAQPDQSESELVNQIIEQLIKKEKVYLAWVPAHK
GIGGNEQVDKLVSAGIRKVLFLDGID
|
|
|
|---|
| BDBM50288063 |
|---|
| n/a |
|---|
| Name | BDBM50288063 |
|---|
| Synonyms: | (4-Methoxycarbonylmethyl-5-oxo-[1,3]dioxolan-4-yl)-acetic acid 5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-2,5-dihydro-furan-2-ylmethyl ester | CHEMBL78388 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C18H20N2O10 |
|---|
| Mol. Mass. | 424.3588 |
|---|
| SMILES | COC(=O)CC1(CC(=O)OCC2OC(C=C2)n2cc(C)c(=O)[nH]c2=O)OCOC1=O |c:14| |
|---|
| Structure | 
|
|---|
Search and Browse
