| Reaction Details |
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 | Report a problem with these data |
| Target | Gag-Pol polyprotein [489-587] |
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| Ligand | BDBM50288419 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_157739 |
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| Ki | 0.910000±n/a nM |
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| Citation |  Rodgers, JD; Johnson, BL; Wang, H; Greenberg, RA; Erickson-Viitanen, S; Klabe, RM; Cordova, BC; Rayner, MM; Lam, GN; Chang, CH Potent cyclic urea HIV protease inhibitors with benzofused heterocycles as P2/P2′ groups Bioorg Med Chem Lett6:2919-2924 (1996) Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Gag-Pol polyprotein [489-587] |
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| Name: | Gag-Pol polyprotein [489-587] |
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| Synonyms: | Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol |
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| Type: | Enzyme Subunit |
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| Mol. Mass.: | 10781.16 |
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| Organism: | Human immunodeficiency virus type 1 |
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| Description: | P04585[489-587] |
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| Residue: | 99 |
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| Sequence: | PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYD
QILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
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| BDBM50288419 |
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| n/a |
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| Name | BDBM50288419 |
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| Synonyms: | 6-[4,7-dibenzyl-5,6-dihydroxy-2-oxo-3-(2-oxo-2,3-dihydrobenzo[d][1,3]thiazol-6-ylmethyl)-(4R,5S,6S,7R)-1,3-diazepan-1-ylmethyl]-2,3-dihydrobenzo[d][1,3]thiazol-2-one | CHEMBL98785 |
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| Type | Small organic molecule |
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| Emp. Form. | C35H32N4O5S2 |
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| Mol. Mass. | 652.782 |
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| SMILES | O[C@@H]1[C@@H](O)[C@@H](Cc2ccccc2)N(Cc2ccc3[nH]c(=O)sc3c2)C(=O)N(Cc2ccc3[nH]c(=O)sc3c2)[C@@H]1Cc1ccccc1 |
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| Structure | 
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