| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Gag-Pol polyprotein [489-587] |
|---|
| Ligand | BDBM50288428 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_157739 |
|---|
| Ki | 190±n/a nM |
|---|
| Citation |  Rodgers, JD; Johnson, BL; Wang, H; Greenberg, RA; Erickson-Viitanen, S; Klabe, RM; Cordova, BC; Rayner, MM; Lam, GN; Chang, CH Potent cyclic urea HIV protease inhibitors with benzofused heterocycles as P2/P2′ groups Bioorg Med Chem Lett6:2919-2924 (1996) Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Gag-Pol polyprotein [489-587] |
|---|
| Name: | Gag-Pol polyprotein [489-587] |
|---|
| Synonyms: | Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol |
|---|
| Type: | Enzyme Subunit |
|---|
| Mol. Mass.: | 10781.16 |
|---|
| Organism: | Human immunodeficiency virus type 1 |
|---|
| Description: | P04585[489-587] |
|---|
| Residue: | 99 |
|---|
| Sequence: | PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYD
QILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
|
|
|
|---|
| BDBM50288428 |
|---|
| n/a |
|---|
| Name | BDBM50288428 |
|---|
| Synonyms: | (4R,5S,6S,7R)-1,3-Bis-(2-amino-benzothiazol-5-ylmethyl)-4,7-dibenzyl-5,6-dihydroxy-[1,3]diazepan-2-one | CHEMBL330404 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C35H34N6O3S2 |
|---|
| Mol. Mass. | 650.813 |
|---|
| SMILES | Nc1nc2cc(CN3[C@H](Cc4ccccc4)[C@H](O)[C@@H](O)[C@@H](Cc4ccccc4)N(Cc4ccc5sc(N)nc5c4)C3=O)ccc2s1 |
|---|
| Structure | 
|
|---|
Search and Browse
