| Reaction Details |
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 | Report a problem with these data |
| Target | Tryptophan 2,3-dioxygenase |
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| Ligand | BDBM50289138 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_210838 |
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| Ki | 40±n/a nM |
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| Citation |  Madge, DJ; Hazelwood, R; Iyer, R; Jones, HT; Salter, M Novel tryptophan dioxygenase inhibitors and combined tryptophan dioxygenase/5-HT reuptake inhibitors Bioorg Med Chem Lett6:857-860 (1996) Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Tryptophan 2,3-dioxygenase |
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| Name: | Tryptophan 2,3-dioxygenase |
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| Synonyms: | T23O_RAT | TO | TRPO | Tdo | Tdo2 | Tryptamin 2,3-dioxygenase | Tryptophan oxygenase | Tryptophan pyrrolase |
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| Type: | PROTEIN |
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| Mol. Mass.: | 47856.01 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_210838 |
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| Residue: | 406 |
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| Sequence: | MSGCPFSGNSVGYTLKNLSMEDNEEDGAQTGVNRASKGGLIYGDYLQLEKILNAQELQSE
IKGNKIHDEHLFIITHQAYELWFKQILWELDSVREIFQNGHVRDERNMLKVMTRMHRVVV
IFKLLVQQFSVLETMTALDFNDFREYLSPASGFQSLQFRLLENKIGVLQSLRVPYNRKHY
RDNFEGDYNELLLKSEQEQTLLQLVEAWLERTPGLEPHGFNFWGKFEKNILKGLEEEFLK
IQAKKDSEEKEEQMAEFRKQKEVLLCLFDEKRHDYLLSKGERRLSYRALQGALMIYFYRE
EPRFQVPFQLLTSLMDIDTLMTKWRYNHVCMVHRMLGSKAGTGGSSGYYYLRSTVSDRYK
VFVDLFNLSSYLVPRHWIPKMNPIIHKFLYTAEYSDSSYFSSDESD
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| BDBM50289138 |
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| n/a |
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| Name | BDBM50289138 |
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| Synonyms: | 3-((E)-2-Pyridin-3-yl-vinyl)-1H-indole | CHEMBL441669 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H12N2 |
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| Mol. Mass. | 220.2692 |
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| SMILES | C(=C/c1cccnc1)\c1c[nH]c2ccccc12 |
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| Structure | 
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