| Reaction Details |
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 | Report a problem with these data |
| Target | MHC class II antigen |
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| Ligand | BDBM50289266 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_192854 (CHEMBL800187) |
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| IC50 | 170±n/a nM |
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| Citation |  Cunningham, BR; Rivetna, M; Tolman, RL; Flattery, SJ; Nichols, EA; Schwartz, CD; Wicker, LS; Hermes, JD; Jones, AB SAR for MHC class II binding tetrapeptides: Correlation with potential binding site Bioorg Med Chem Lett7:19-24 (1997) Article |
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| More Info.: | Get all data from this article, Assay Method |
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| MHC class II antigen |
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| Name: | MHC class II antigen |
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| Synonyms: | DR-1 | DR1 | HLA class II histocompatibility antigen DRB1-1 | HLA class II histocompatibility antigen, DRB1-1 beta chain | Human leukocyte antigen DR beta chain | MHC class I antigen DRB1*1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 29917.79 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_192854 |
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| Residue: | 266 |
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| Sequence: | MVCLKLPGGSCMTALTVTLMVLSSPLALAGDTRPRFLWQLKFECHFFNGTERVRLLERCI
YNQEESVRFDSDVGEYRAVTELGRPDAEYWNSQKDLLEQRRAAVDTYCRHNYGVGESFTV
QRRVEPKVTVYPSKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNG
DWTFQTLVMLETVPRSGEVYTCQVEHPSVTSPLTVEWRARSESAQSKMLSGVGGFVLGLL
FLGAGLFIYFRNQKGHSGLQPTGFLS
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| BDBM50289266 |
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| n/a |
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| Name | BDBM50289266 |
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| Synonyms: | 6-Amino-hexanoic acid (1-{(S)-1-[1-((S)-(S)-1-carbamoyl-3-methyl-butylcarbamoyl)-ethylcarbamoyl]-2-methyl-propylcarbamoyl}-2-phenyl-ethyl)-amide | CHEMBL420380 |
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| Type | Small organic molecule |
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| Emp. Form. | C29H48N6O5 |
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| Mol. Mass. | 560.7286 |
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| SMILES | CC(C)C[C@H](NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CCCCCN)C(C)C)C(N)=O |
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| Structure | 
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