| Reaction Details |
|---|
 | Report a problem with these data |
| Target | MHC class II antigen |
|---|
| Ligand | BDBM50289258 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_192854 (CHEMBL800187) |
|---|
| IC50 | 16.0±n/a nM |
|---|
| Citation |  Cunningham, BR; Rivetna, M; Tolman, RL; Flattery, SJ; Nichols, EA; Schwartz, CD; Wicker, LS; Hermes, JD; Jones, AB SAR for MHC class II binding tetrapeptides: Correlation with potential binding site Bioorg Med Chem Lett7:19-24 (1997) Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| MHC class II antigen |
|---|
| Name: | MHC class II antigen |
|---|
| Synonyms: | DR-1 | DR1 | HLA class II histocompatibility antigen DRB1-1 | HLA class II histocompatibility antigen, DRB1-1 beta chain | Human leukocyte antigen DR beta chain | MHC class I antigen DRB1*1 |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 29917.79 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_192854 |
|---|
| Residue: | 266 |
|---|
| Sequence: | MVCLKLPGGSCMTALTVTLMVLSSPLALAGDTRPRFLWQLKFECHFFNGTERVRLLERCI
YNQEESVRFDSDVGEYRAVTELGRPDAEYWNSQKDLLEQRRAAVDTYCRHNYGVGESFTV
QRRVEPKVTVYPSKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNG
DWTFQTLVMLETVPRSGEVYTCQVEHPSVTSPLTVEWRARSESAQSKMLSGVGGFVLGLL
FLGAGLFIYFRNQKGHSGLQPTGFLS
|
|
|
|---|
| BDBM50289258 |
|---|
| n/a |
|---|
| Name | BDBM50289258 |
|---|
| Synonyms: | (S)-2-((S)-3-Carbamoyl-2-{(S)-2-[((R)-2-ethoxycarbonylamino-3-naphthalen-1-yl-propionyl)-methyl-amino]-5-guanidino-pentanoylamino}-propionylamino)-3-methyl-butyric acid methyl ester | CHEMBL80447 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C33H48N8O8 |
|---|
| Mol. Mass. | 684.783 |
|---|
| SMILES | CCOC(=O)N[C@H](Cc1cccc2ccccc12)C(=O)N(C)[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](C(C)C)C(=O)OC |
|---|
| Structure | 
|
|---|
Search and Browse
