new BindingDB logo
myBDB logout
Reaction Details
Report a problem with these data
TargetHLA class II histocompatibility antigen DRB1-1
LigandBDBM50289261
Substrate/Competitorn/a
Meas. Tech.ChEBML_192856
IC50 390±n/a nM
Citation Cunningham BRRivetna MTolman RLFlattery SJNichols EASchwartz CDWicker LSHermes JDJones AB SAR for MHC class II binding tetrapeptides: Correlation with potential binding site Bioorg Med Chem Lett 7:19-24 (1997)    Article
More Info.:Get all data from this article,  Assay Method
 
HLA class II histocompatibility antigen DRB1-1
Name:Human leukocyte antigen DR beta chain
Synonyms:DR-1 | DR1 | HLA class II histocompatibility antigen, DRB1-1 beta chain | MHC class I antigen DRB1*1
Type:PROTEIN
Mol. Mass.:29917.79
Organism:Homo sapiens (Human)
Description:ChEMBL_192854
Residue:266
Sequence:
MVCLKLPGGSCMTALTVTLMVLSSPLALAGDTRPRFLWQLKFECHFFNGTERVRLLERCI
YNQEESVRFDSDVGEYRAVTELGRPDAEYWNSQKDLLEQRRAAVDTYCRHNYGVGESFTV
QRRVEPKVTVYPSKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNG
DWTFQTLVMLETVPRSGEVYTCQVEHPSVTSPLTVEWRARSESAQSKMLSGVGGFVLGLL
FLGAGLFIYFRNQKGHSGLQPTGFLS
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50289261
n/a
NameBDBM50289261
Synonyms:Acetic acid ((S)-1-{(S)-1-[(S)-1-((S)-1-carbamoyl-3-methyl-butylcarbamoyl)-ethylcarbamoyl]-2-methyl-propylcarbamoyl}-2-phenyl-ethylcarbamoyl)-methyl ester | CHEMBL310163
TypeSmall organic molecule
Emp. Form.C27H41N5O7
Mol. Mass.547.6437
SMILESCC(C)C[C@H](NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)COC(C)=O)C(C)C)C(N)=O
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least: