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TargetHLA class II histocompatibility antigen DRB1-1
LigandBDBM50289252
Substrate/Competitorn/a
Meas. Tech.ChEMBL_192854
IC50 22±n/a nM
Citation Cunningham BRRivetna MTolman RLFlattery SJNichols EASchwartz CDWicker LSHermes JDJones AB SAR for MHC class II binding tetrapeptides: Correlation with potential binding site Bioorg Med Chem Lett 7:19-24 (1997)    Article
More Info.:Get all data from this article,  Assay Method
 
HLA class II histocompatibility antigen DRB1-1
Name:Human leukocyte antigen DR beta chain
Synonyms:DR-1 | DR1 | HLA class II histocompatibility antigen, DRB1-1 beta chain | MHC class I antigen DRB1*1
Type:PROTEIN
Mol. Mass.:29917.79
Organism:Homo sapiens (Human)
Description:ChEMBL_192854
Residue:266
Sequence:
MVCLKLPGGSCMTALTVTLMVLSSPLALAGDTRPRFLWQLKFECHFFNGTERVRLLERCI
YNQEESVRFDSDVGEYRAVTELGRPDAEYWNSQKDLLEQRRAAVDTYCRHNYGVGESFTV
QRRVEPKVTVYPSKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNG
DWTFQTLVMLETVPRSGEVYTCQVEHPSVTSPLTVEWRARSESAQSKMLSGVGGFVLGLL
FLGAGLFIYFRNQKGHSGLQPTGFLS
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  Blast E-value cutoff:
BDBM50289252
n/a
NameBDBM50289252
Synonyms:(S)-2-((S)-2-{(S)-2-[(S)-2-(3-Ethyl-ureido)-3-phenyl-propionylamino]-3-methyl-butyrylamino}-propionylamino)-4-methyl-pentanoic acid amide | CHEMBL81463
TypeSmall organic molecule
Emp. Form.C26H42N6O5
Mol. Mass.518.6489
SMILESCCNC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(N)=O
Structure
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