Reaction Details |
| Report a problem with these data |
Target | Gag-Pol polyprotein [489-587] |
---|
Ligand | BDBM33 |
---|
Substrate/Competitor | n/a |
---|
Meas. Tech. | ChEBML_79984 |
---|
Ki | 0.470000±n/a nM |
---|
Citation | Smallheer, JM; McHugh, RJ; Chang, CH; Kaltenbach, RF; Worley, TV; Klabe, RM; Bacheler, LT; Rayner, MM; Erickson-Viitanen, S; Seitz, SP Functionalized aliphatic P2/P2′ analogs of HIV-1 protease inhibitor DMP323 Bioorg Med Chem Lett7:1365-1370 (1997) Article |
---|
More Info.: | Get all data from this article, Assay Method |
---|
|
Gag-Pol polyprotein [489-587] |
---|
Name: | Gag-Pol polyprotein [489-587] |
Synonyms: | Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol |
Type: | Enzyme Subunit |
Mol. Mass.: | 10781.16 |
Organism: | Human immunodeficiency virus type 1 |
Description: | P04585[489-587] |
Residue: | 99 |
Sequence: | PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYD
QILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
|
|
|
BDBM33 |
---|
n/a |
---|
Name | BDBM33 |
Synonyms: | (4R,5S,6S,7R)-4,7-dibenzyl-5,6-dihydroxy-1,3-bis(6-hydroxyhexyl)-1,3-diazepan-2-one | DMPC Cyclic Urea 13 |
Type | n/a |
Emp. Form. | C31H46N2O5 |
Mol. Mass. | 526.7073 |
SMILES | OCCCCCCN1[C@H](Cc2ccccc2)[C@H](O)[C@@H](O)[C@@H](Cc2ccccc2)N(CCCCCCO)C1=O |
Structure |
|