| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Beta-lactamase TEM |
|---|
| Ligand | BDBM50290038 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_40561 |
|---|
| IC50 | 90000±n/a nM |
|---|
| Citation |  Pfaendler, HR; Weishaupt, R; Medicus, C Synthesis and biological activity of novel penem sulfoxides and sulfones Bioorg Med Chem Lett7:2217-2222 (1997) Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Beta-lactamase TEM |
|---|
| Name: | Beta-lactamase TEM |
|---|
| Synonyms: | BLAT_ECOLX | Bacterial beta-lactamase TEM | Beta-lactamase (TEM-1) | Beta-lactamase TEM | Beta-lactamase TEM-1 | Beta-lactamase TEM-1b | Beta-lactamase TEM1D | Beta-lactamase TEM1E | Beta-lactamase TEM1F | TEM beta lactamase | TEM extended-spectrum beta-lactamase | TEM-1 beta-lactamase | bla |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 31512.33 |
|---|
| Organism: | Escherichia coli |
|---|
| Description: | P62593 |
|---|
| Residue: | 286 |
|---|
| Sequence: | MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRP
EERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVREL
CSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTM
PAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGS
RGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW
|
|
|
|---|
| BDBM50290038 |
|---|
| n/a |
|---|
| Name | BDBM50290038 |
|---|
| Synonyms: | CHEMBL419441 | Potassium; (5R,6S)-3-tert-butyl-6-((R)-1-hydroxy-ethyl)-4,7-dioxo-4lambda*4*-thia-1-aza-bicyclo[3.2.0]hept-2-ene-2-carboxylate |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C12H16NO5S |
|---|
| Mol. Mass. | 286.325 |
|---|
| SMILES | C[C@@H](O)[C@@H]1[C@@H]2N(C1=O)C(C([O-])=O)=C(S2=O)C(C)(C)C |c:12| |
|---|
| Structure | 
|
|---|
Search and Browse
