| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Matrix metalloproteinase-9 |
|---|
| Ligand | BDBM50290163 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_105547 |
|---|
| Ki | 290±n/a nM |
|---|
| Citation |  Decicco, CP; Seng, JL; Kennedy, KE; Covington, MB; Welch, PK; Arner, EC; Magolda, RL; Nelson, DJ Amide surrogates of matrix metalloproteinase inhibitors: Urea and sulfonamide mimics Bioorg Med Chem Lett7:2331-2336 (1997) Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Matrix metalloproteinase-9 |
|---|
| Name: | Matrix metalloproteinase-9 |
|---|
| Synonyms: | 67 kDa matrix metalloproteinase-9 | 82 kDa matrix metalloproteinase-9 | 92 kDa gelatinase | 92 kDa type IV collagenase | CLG4B | GELB | Gelatinase B | MMP-9 | MMP9 | MMP9_HUMAN | Matrix metalloproteinase 9 (MMP-9) | Matrix metalloproteinase-9 (MMP-9) | Matrix metalloproteinase-9 (MMP9) |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 78452.28 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P14780 |
|---|
| Residue: | 707 |
|---|
| Sequence: | MSLWQPLVLVLLVLGCCFAAPRQRQSTLVLFPGDLRTNLTDRQLAEEYLYRYGYTRVAEM
RGESKSLGPALLLLQKQLSLPETGELDSATLKAMRTPRCGVPDLGRFQTFEGDLKWHHHN
ITYWIQNYSEDLPRAVIDDAFARAFALWSAVTPLTFTRVYSRDADIVIQFGVAEHGDGYP
FDGKDGLLAHAFPPGPGIQGDAHFDDDELWSLGKGVVVPTRFGNADGAACHFPFIFEGRS
YSACTTDGRSDGLPWCSTTANYDTDDRFGFCPSERLYTQDGNADGKPCQFPFIFQGQSYS
ACTTDGRSDGYRWCATTANYDRDKLFGFCPTRADSTVMGGNSAGELCVFPFTFLGKEYST
CTSEGRGDGRLWCATTSNFDSDKKWGFCPDQGYSLFLVAAHEFGHALGLDHSSVPEALMY
PMYRFTEGPPLHKDDVNGIRHLYGPRPEPEPRPPTTTTPQPTAPPTVCPTGPPTVHPSER
PTAGPTGPPSAGPTGPPTAGPSTATTVPLSPVDDACNVNIFDAIAEIGNQLYLFKDGKYW
RFSEGRGSRPQGPFLIADKWPALPRKLDSVFEERLSKKLFFFSGRQVWVYTGASVLGPRR
LDKLGLGADVAQVTGALRSGRGKMLLFSGRRLWRFDVKAQMVDPRSASEVDRMFPGVPLD
THDVFQYREKAYFCQDRFYWRVSSRSELNQVDQVGYVTYDILQCPED
|
|
|
|---|
| BDBM50290163 |
|---|
| n/a |
|---|
| Name | BDBM50290163 |
|---|
| Synonyms: | 3-[(S)-2-(4-Methoxy-phenyl)-1-methylcarbamoyl-ethylsulfamoyl]-nonanoic acid | CHEMBL311393 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C20H32N2O6S |
|---|
| Mol. Mass. | 428.543 |
|---|
| SMILES | CCCCCCC(CC(O)=O)S(=O)(=O)N[C@@H](Cc1ccc(OC)cc1)C(=O)NC |
|---|
| Structure | 
|
|---|
Search and Browse
