| Reaction Details |
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 | Report a problem with these data |
| Target | Acetylcholine receptor subunit alpha |
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| Ligand | BDBM50049756 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_223071 |
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| EC50 | 34000±n/a nM |
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| Citation |  Elliott, RL; Ryther, KB; Anderson, DJ; Piattoni-Kaplan, M; Kuntzweiler, TA; Donnelly-Roberts, D; Arneric, SP; Holladay, MW Novel 2-(2′-furo[3,2-b]pyridinyl) pyrrolidines: potent neuronal nicotinic acetylcholine receptor ligands Bioorg Med Chem Lett7:2703-2708 (1997) Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Acetylcholine receptor subunit alpha |
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| Name: | Acetylcholine receptor subunit alpha |
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| Synonyms: | ACHA_HUMAN | ACHRA | Acetylcholine receptor protein alpha chain | Acetylcholine receptor subunit alpha | CHNRA | CHRNA1 | Cholinergic, Nicotinic Alpha1Beta1DeltaGamma | Cholinergic, Nicotinic Alpha1Beta2 | Nicotinic acetylcholine receptor alpha-1/beta-1 | Nicotinic acetylcholine receptor alpha-1/beta-1/delta/epsilon | Nicotinic acetylcholine receptor alpha2/beta4 | alpha-1 Nicotinic AChR | n-AChR |
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| Type: | Ion channel |
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| Mol. Mass.: | 54542.01 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 482 |
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| Sequence: | MEPWPLLLLFSLCSAGLVLGSEHETRLVAKLFKDYSSVVRPVEDHRQVVEVTVGLQLIQL
INVDEVNQIVTTNVRLKQGDMVDLPRPSCVTLGVPLFSHLQNEQWVDYNLKWNPDDYGGV
KKIHIPSEKIWRPDLVLYNNADGDFAIVKFTKVLLQYTGHITWTPPAIFKSYCEIIVTHF
PFDEQNCSMKLGTWTYDGSVVAINPESDQPDLSNFMESGEWVIKESRGWKHSVTYSCCPD
TPYLDITYHFVMQRLPLYFIVNVIIPCLLFSFLTGLVFYLPTDSGEKMTLSISVLLSLTV
FLLVIVELIPSTSSAVPLIGKYMLFTMVFVIASIIITVIVINTHHRSPSTHVMPNWVRKV
FIDTIPNIMFFSTMKRPSREKQDKKIFTEDIDISDISGKPGPPPMGFHSPLIKHPEVKSA
IEGIKYIAETMKSDQESNNAAAEWKYVAMVMDHILLGVFMLVCIIGTLAVFAGRLIELNQ
QG
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| BDBM50049756 |
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| n/a |
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| Name | BDBM50049756 |
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| Synonyms: | 3-((S)-1-Methyl-pyrrolidin-2-ylmethoxy)-pyridine | A-84543 | CHEMBL84149 |
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| Type | Small organic molecule |
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| Emp. Form. | C11H16N2O |
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| Mol. Mass. | 192.2575 |
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| SMILES | CN1CCC[C@H]1COc1cccnc1 |
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| Structure | 
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