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TargetHuman immunodeficiency virus type 1 protease
LigandBDBM50291060
Substrate/Competitorn/a
Meas. Tech.ChEBML_157558
Ki 2.1±n/a nM
Citation Schwartz TMBundy GLStrohbach JWThaisrivongs SJohnson PDSkulnick HITomich PKLynn JCChong KTHinshaw RRRaub TJPadbury GEToth LN Synthesis and pharmacological evaluation of sulfone substituted HIV protease inhibitors Bioorg Med Chem Lett 7:399-402 (1997)    Article
More Info.:Get all data from this article,  Assay Method
 
Human immunodeficiency virus type 1 protease
Name:Human immunodeficiency virus type 1 protease
Synonyms:Pol polyprotein
Type:Enzyme Subunit
Mol. Mass.:10781.16
Organism:Human immunodeficiency virus type 1
Description:n/a
Residue:99
Sequence:
PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYD
QILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
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BDBM50291060
n/a
NameBDBM50291060
Synonyms:3-{Cyclopropyl-[3-(4-fluoro-benzenesulfonylmethyl)-phenyl]-methyl}-4-hydroxy-5,6,7,8,9,10-hexahydro-cycloocta[b]pyran-2-one | CHEMBL131064
TypeSmall organic molecule
Emp. Form.C28H29FO5S
Mol. Mass.496.59
SMILESOc1c2CCCCCCc2oc(=O)c1C(C1CC1)c1cccc(CS(=O)(=O)c2ccc(F)cc2)c1
Structure
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